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  2. Hypogammaglobulinemia - Wikipedia

    en.wikipedia.org/wiki/Hypogammaglobulinemia

    Hypogammaglobulinemia is an immune system disorder in which not enough gamma globulins are produced in the blood (thus hypo-+ gamma + globulin + -emia).This results in a lower antibody count, which impairs the immune system, increasing risk of infection.

  3. X-linked agammaglobulinemia - Wikipedia

    en.wikipedia.org/wiki/X-linked_agammaglobulinemia

    X-chromosome. Most antibodies are gamma globulins. Antibodies are made mainly by plasma cells, which are daughter cells of the B cell line.The Btk enzyme plays an essential role in the maturation of B cells in the bone marrow, and when mutated, immature pro-B lymphocytes are unable to develop into pre-B lymphocytes, which normally develop into mature (naive) B cells that leave the bone marrow ...

  4. Signs and symptoms of Graves' disease - Wikipedia

    en.wikipedia.org/wiki/Signs_and_symptoms_of...

    Abnormal breast enlargement in men [12] Augmented calcium levels in the blood (by as much as 25% – known as hypercalcaemia). This can cause stomach upset, excessive urination, and impaired kidney function. [13] Diabetes may be activated or intensified, and its control worsened. The diabetes is ameliorated or may disappear when the ...

  5. What Is Low Testosterone & What Causes It? - AOL

    www.aol.com/lifestyle/low-testosterone-causes...

    In one study of men aged 65 years and over, those with lower testosterone levels experienced reduced sleep efficiency, woke up more in the middle of the night, and had less time in slow-wave sleep ...

  6. Aging-associated diseases - Wikipedia

    en.wikipedia.org/wiki/Aging-associated_diseases

    Over time, these processes can stiffen the vasculature. For these reasons, older age is listed as a major risk factor for atherosclerosis. [ 16 ] Specifically, the risk of atherosclerosis increases for men above 45 years of age and women above 55 years of age.

  7. Coombs test - Wikipedia

    en.wikipedia.org/wiki/Coombs_test

    Coombs reagent (also known as Coombs antiglobulin or antihuman globulin) is used in both the direct Coombs test and the indirect Coombs test. Coombs reagent is antihuman globulin . It is made by injecting human globulin into animals, which produce polyclonal antibodies specific for human immunoglobulins and human complement system factors.

  8. Late-onset hypogonadism - Wikipedia

    en.wikipedia.org/wiki/Late-onset_hypogonadism

    As of 2016, the International Society for the Study of the Aging Male defines late-onset hypogonadism as a series of symptoms in older adults related to testosterone deficiency that combines features of both primary and secondary hypogonadism; the European Male Aging Study (a prospective study of ~3000 men) [10] defined the condition by the presence of at least three sexual symptoms (e.g ...

  9. Low Testosterone in Men Linked with Higher Risk of Death - AOL

    www.aol.com/lifestyle/low-testosterone-men...

    After their analysis, they determined that men with low total testosterone (below 7.4 nmol/L [213 ng/dL]) had a greater risk of dying from any cause. Further, those with very low levels of ...