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On 9 November 2012, Indian drugmaker Ranbaxy Laboratories Ltd. voluntarily recalled 10-, 20- and 40-mg doses of its generic version of atorvastatin in the United States. [ 134 ] [ 135 ] [ 136 ] The lots of atorvastatin, packaged in bottles of 90 and 500 tablets, were recalled due to possible contamination with very small glass particles similar ...
Statins are a type of medication that can help lower a person’s “bad” cholesterol, helping reduce their risk for cardiovascular disease.
The class is on the World Health Organization's List of Essential Medicines with simvastatin being the listed medicine. [10] In 2005, sales were estimated at US$18.7 billion in the United States. [11] The best-selling statin is atorvastatin, also known as Lipitor, which in 2003 became the best-selling pharmaceutical in history. [12]
Red yeast rice [10] is the natural source from which statins were discovered, but the FDA currently disallows any RYR with significant amounts of statin to be sold as a dietary supplement [11] Boswellia serrata [12] L-arginine may enhance the effects of a Statin, but will not lead to a reduction in cholesterol alone. [13] Flaxseed oil [14]
Ezetimibe/atorvastatin (trade names Liptruzet, Atozet) is a cholesterol lowering combination drug. In the United States, it was approved in May 2013, by the Food and Drug Administration for the treatment of elevated low-density lipoprotein (LDL) in patients with primary or mixed hyperlipidemia as adjunctive therapy to diet. [ 1 ]
10: Ten receive the treatment, and ten receive a control. Two improve with the treatment and eight do not. In the control group, one improves and nine do not. Therefore, the treatment was more helpful than the control in only one of ten cases, and was not helpful is nine of ten. NNT is 1/(0.9 – 0.8), which is 10.
The abnormal cold could also dip far enough south to wreak havoc on Florida’s highly sensitive citrus crops and cause iguanas to plummet from trees. The cold is likely to stick around through ...
Food intake prior to testing may cause elevated levels, up to 20%. Normal level is defined as less than 150 mg/dL. [46] Borderline high is defined as 150 to 199 mg/dL. [46] High level is between 200 and 499 mg/dL. [46] Greater than 500 mg/dL is defined as very high, [46] and is associated with pancreatitis and requires medical treatment. [47]
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