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  2. Inclusion body myositis - Wikipedia

    en.wikipedia.org/wiki/Inclusion_body_myositis

    Weakness comes on slowly (over months to years) in an asymmetric manner and progresses steadily, leading to severe weakness and wasting of arm and leg muscles. IBM is more common in men than women. [10] Patients may become unable to perform activities of daily living and most require assistive devices within 5 to 10 years of symptom onset.

  3. Postorgasmic illness syndrome - Wikipedia

    en.wikipedia.org/wiki/Postorgasmic_illness_syndrome

    POIS symptoms, which are called a "POIS attack", [1] can include some combination of the following: cognitive dysfunction, aphasia, severe muscle pain throughout the body, severe fatigue, weakness, and flu-like or allergy-like symptoms, [4] such as sneezing, itchy eyes, and nasal irritation.

  4. Lambert–Eaton myasthenic syndrome - Wikipedia

    en.wikipedia.org/wiki/Lambert–Eaton_myasthenic...

    Weakness of the eye muscles is uncommon. Some may have double vision, drooping of the eyelids and difficulty swallowing, [4] but generally only together with leg weakness; this too distinguishes LEMS from myasthenia gravis, in which eye signs are much more common. [3] In the advanced stages of the disease, weakness of the respiratory muscles ...

  5. Signs and symptoms of multiple sclerosis - Wikipedia

    en.wikipedia.org/wiki/Signs_and_symptoms_of...

    Multiple sclerosis can cause a variety of symptoms: changes in sensation (hypoesthesia), muscle weakness, abnormal muscle spasms, or difficulty moving; difficulties with coordination and balance; problems in speech or swallowing , visual problems (nystagmus, optic neuritis, phosphenes or diplopia), fatigue and acute or chronic pain syndromes ...

  6. Muscle weakness - Wikipedia

    en.wikipedia.org/wiki/Muscle_weakness

    Muscle weakness can also be classified as either "proximal" or "distal" based on the location of the muscles that it affects. Proximal muscle weakness affects muscles closest to the body's midline, while distal muscle weakness affects muscles further out on the limbs. Proximal muscle weakness can be seen in Cushing's syndrome [18] and ...

  7. Neuromuscular disease - Wikipedia

    en.wikipedia.org/wiki/Neuromuscular_disease

    Symptoms of neuromuscular disease may include numbness, paresthesia, muscle atrophy, a pseudoathletic appearance, exercise intolerance, myalgia (muscle pain), fasciculations (muscle twitches), myotonia (delayed muscle relaxation), hypotonia (lack of resistance to passive movement), fixed muscle weakness (a static symptom), or premature muscle ...

  8. Myopathy - Wikipedia

    en.wikipedia.org/wiki/Myopathy

    Polymyositis produces muscle weakness. It can often be treated by drugs like corticosteroids or immunosuppressants. Inclusion body myositis is a slowly progressive disease that produces weakness of hand grip and straightening of the knees. No effective treatment is known. (M60.9) Benign acute childhood myositis (M61) Myositis ossificans

  9. Spinal and bulbar muscular atrophy - Wikipedia

    en.wikipedia.org/wiki/Spinal_and_bulbar_muscular...

    Muscle strength declines slowly, at a rate of approximately 2% per year based on quantitative muscle assessment. [11] [12] Muscle weakness often begins in proximal muscles, with most patients first noticing weakness in their lower limbs. [3] [13] Tremor, fasciculations, and cramps are common early symptoms of SBMA.

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