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The appendix, therefore, may act as a "safe house" for beneficial bacteria. [14] This reservoir of bacteria could then serve to repopulate the gut flora in the digestive system following a bout of dysentery or cholera or to boost it following a milder gastrointestinal illness. [15]
Ileum, caecum and colon of rabbit, showing Appendix vermiformis on fully functional caecum The human vermiform appendix on the vestigial caecum. The appendix was once believed to be a vestige of a redundant organ that in ancestral species had digestive functions, much as it still does in extant species in which intestinal flora hydrolyze cellulose and similar indigestible plant materials. [10]
In humans, the vermiform appendix is sometimes called a vestigial structure as it has lost much of its ancestral digestive function. Vestigiality is the retention, during the process of evolution, of genetically determined structures or attributes that have lost some or all of the ancestral function in a given species. [1]
The appendix, long misunderstood as a vestigial organ, is now recognized as a key MALT structure, playing an essential role in B-lymphocyte-mediated immune responses, hosting extrathymically derived T-lymphocytes, regulating pathogens through its lymphatic vessels, and potentially producing early defenses against diseases. [1]
Coming off the side of the cecum (the tiny tail piece) is the appendix. It is a small organ attached to the large intestine in the lower right side of the abdomen. Anatomists and medical professionals have traditionally considered the appendix a vestigial organ. Later research suggests that it may have an immunological function. [13]
Location of the appendix in the digestive system 3D model of appendicitis. Acute appendicitis seems to be the result of a primary obstruction of the appendix. [20] [10] Once this obstruction occurs, the appendix becomes filled with mucus and swells. This continued production of mucus leads to increased pressures within the lumen and the walls ...
Specifically, the cecum and appendix are formed by the enlargement of the postarterial segment of the midgut loop. The proximal part of the bud grows rapidly to form the cecum. The lateral wall of the cecum grows much more rapidly than the medial wall, with the result that the point of attachment of the appendix comes to lie on the medial side.
The human digestive system consists of the gastrointestinal tract plus the accessory organs of digestion (the tongue, salivary glands, pancreas, liver, and gallbladder). Digestion involves the breakdown of food into smaller and smaller components, until they can be absorbed and assimilated into the body.