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When of gradual onset, symptoms may include loss of bladder control, mild lower abdominal pain, and a weak urine stream. [1] Those with long-term problems are at risk of urinary tract infections. [1] Causes include blockage of the urethra, nerve problems, certain medications, and weak bladder muscles. [1]
Mirabegron, sold under the brand name Myrbetriq among others, is a medication used to treat overactive bladder. [5] Its benefits are similar to antimuscarinic medication such as solifenacin or tolterodine. [6] It is taken by mouth. [5] Common side effects include high blood pressure, headaches, and urinary tract infections. [5]
Tolterodine, sold under the brand name Detrol among others, is a medication used to treat frequent urination, urinary incontinence, or urinary urgency. [5] Effects are seen within an hour. [6] It is taken by mouth. [6] [7] Common side effects include headache, dry mouth, constipation, and dizziness. [6]
A number of medications exist to treat urinary incontinence including: fesoterodine, tolterodine and oxybutynin. [59] These medications work by relaxing smooth muscle in the bladder. [60] [61] [62] While some of these medications appear to have a small benefit, the risk of side effects are a concern. [59]
"The longer the bladder is full, the greater the likelihood of leakage of urine," Dr. Fromer says. In the short-term, you might feel embarrassed that you "peed your pants" and need a swift outfit ...
The bladder wall muscle overactivity results in sporadic bladder muscle contraction, which increases pressure in the bladder and decreases the volume of urine the bladder can hold. [2] If NDO is not treated, increased pressure in the bladder can put the upper urinary tract at risk of harm, including possible permanent damage to the kidneys. [ 2 ]
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