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In this affidavit, Bugie stated that she was informed about streptomycin by Waksman and Shatz and had no part in the discovery of streptomycin. [18] Bugie was, however, later quoted by her daughters as having said that if the women's liberation movement had been present, she would have received credit towards the patent on streptomycin. [ 1 ]
Schatz was the lead author of the paper on streptomycin discovery with Bugie as the second. Bugie was excluded from the patent due to Waksman's impression that she would "just get married." [16] Years later Bugie told her daughters, "If women's lib had been around, my name would have been on the patent." [34]
Of these, streptomycin and neomycin found extensive application in the treatment of numerous infectious diseases. Streptomycin was the first antibiotic cure for tuberculosis (TB). In 1952 Waksman was the recipient of the Nobel Prize in Physiology or Medicine in recognition "for his discovery of streptomycin, the first antibiotic active against ...
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In 1944 Albert Schatz, Elizabeth Bugie, and Selman Waksman isolated streptomycin produced by a bacterial strain Streptomyces griseus. Streptomycin was the first effective antibiotic against M. tuberculosis. [113] This discovery is generally considered the beginning of the modern era of tuberculosis. [113]
Selman Abraham Waksman (July 22, 1888 – August 16, 1973) was a Jewish American inventor, Nobel Prize laureate, biochemist and microbiologist whose research into the decomposition of organisms that live in soil enabled the discovery of streptomycin and several other antibiotics.
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Streptomycin is the first-in-class aminoglycoside antibiotic. It is derived from Streptomyces griseus and is the earliest modern agent used against tuberculosis. Streptomycin lacks the common 2-deoxystreptamine moiety (image right, below) present in most other members of this class.