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A syrette is a single-use device for injecting liquid through a needle. It is similar to a syringe except that it has a sealed squeeze tube instead of a rigid tube and piston . It was developed by the pharmaceutical manufacturer E.R. Squibb & Sons (eventually merged into the current day Bristol-Myers Squibb ) just prior to World War II (WWII).
Animal and human studies and clinical experience back up the contention that morphine is one of the most euphoric drugs known, and via all but the IV route heroin and morphine cannot be distinguished according to studies because heroin is a prodrug for the delivery of systemic morphine.
Laudanum is a tincture of opium containing approximately 10% powdered opium by weight (the equivalent of 1% morphine). [1] Laudanum is prepared by dissolving extracts from the opium poppy (Papaver somniferum) in alcohol ().
The drug or other substance has a currently accepted medical use in treatment in the United States or a currently accepted medical use with severe restrictions. Abuse of the drug or other substances may lead to severe psychological or physical dependence. The complete list of Schedule II substances is as follows.
Carbonate derivatives of 14β-hydroxycodeine "viz., 14β-hydroxy-6-O-(methoxycarbonyl)codeine, 6-O-methoxycarbonyl-14β-(methoxycarbonyloxy)codeine, and 14β-acetoxy-6-O-methoxy-carbonylcodeine, potential substrates for ring C modification in morphinane (sic) alkaloids, were synthesized for the first time."
Brompton cocktail, sometimes called Brompton mixture or Brompton's cocktail, was an elixir meant for use as a pain suppressant dosed for prophylaxis.Made from morphine or diacetylmorphine (heroin), cocaine, highly pure ethyl alcohol (some recipes specify gin), and sometimes with chlorpromazine (Thorazine) to counteract nausea, it was given to terminally ill individuals (especially cancer ...
Dihydromorphine acts as an agonist at the μ-opioid with a K i value of 2.5 nM compared to 4.9 nM of morphine, δ-opioid with a K i value of 137 nM compared to 273 nM of morphine and κ-opioid with a K i value of 223 nM compared to 227 nM of morphine. Dihydromorphine is therefore slightly more μ-selective than morphine.
Hydromorphone, also known as dihydromorphinone, and sold under the brand name Dilaudid among others, is a morphinan opioid used to treat moderate to severe pain. [7] Typically, long-term use is only recommended for pain due to cancer. [9] It may be used by mouth or by injection into a vein, muscle, or under the skin. [7]