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RNFL asymmetry has been proposed as a strong indicator of optic neuritis, [7] [8] with one small study proposing that asymmetry of 5–6μm was "a robust structural threshold for identifying the presence of a unilateral optic nerve lesion in MS." [9] Optic neuritis is often associated with multiple sclerosis, and RNFL data may indicate the pace ...
Visual field-right superior quadrantanopia. Lesions of right temporal lobe (meyer's Loop) of the optic radiation on one side produces a loss of the upper, outer quadrant of vision on the contralateral side, known as homonymous superior quadrantanopia or superior quadrantic hemianopia. [25] This is also known as pie in the sky disorder. [3]
The Pancoast tumor was first described by Hare in 1838 as a "tumor involving certain nerves". [2] It was not until 1924 that the tumor was described in further detail, when Henry Pancoast, a radiologist from Philadelphia, published an article in which he reported and studied many cases of apical chest tumors that all shared the same radiographic findings and associated clinical symptoms, such ...
Major symptoms are sudden loss of vision (partial or complete), sudden blurred or "foggy" vision, and; pain on movement of the affected eye. [4] [5] [2]Many patients with optic neuritis may lose some of their color vision in the affected eye (especially red), with colors appearing subtly washed out compared to the other eye.
It is a paraneoplastic type of autoimmune retinopathy. [2] It may be seen in association with various cancers including non-small cell lung cancer, breast cancer, gynacological cancers, tumors of the hematopoietic and lymphoid tissues, basal cell carcinoma, colon cancer, kidney cancer, prostate cancer and pancreatic cancer.
The optic nerve contains axons of nerve cells that emerge from the retina, leave the eye at the optic disc, and go to the visual cortex where input from the eye is processed into vision. There are 1.2 million optic nerve fibers that derive from the retinal ganglion cells of the inner retina. [2] Damage to the optic nerve can have different causes:
A lesion in the temporal lobe that results in damage to Meyer's loop causes a characteristic loss of vision in a superior quadrant (quadrantanopia or "pie in the sky" defect.) Fibers from the superior retina* travel straight back through the parietal lobe to the occipital lobe in the retrolenticular limb of the internal capsule to the visual ...
[1] [2] This reduced axonal transport can then cause swelling or bulging on the surface layer of the retina, increasing the potential for nerve fiber damage. [ 2 ] The presence of cotton wool spots may resolve independently over time, typically in 4–12 weeks, or may depend on the underlying disease causing the condition.
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