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Adipsia can tend to result from lesions to hypothalamic regions involved in thirst regulation. These lesions can be congenital, acquired, trauma, or even surgery. Lesions or injuries to those hypothalamic regions cause adipsia because the lesions cause defects in the thirst regulating center which can lead to adipsia.
Thirst (1886), by William-Adolphe Bouguereau. Thirst is the craving for potable fluids, resulting in the basic instinct of animals to drink. It is an essential mechanism involved in fluid balance. [1] It arises from a lack of fluids or an increase in the concentration of certain osmolites, such as sodium.
This can be due to injury to the hypothalamus or pituitary gland or due to genetics. [1] Nephrogenic DI (NDI), also known as arginine vasopressin resistance (AVP-R), [5] occurs when the kidneys do not respond properly to vasopressin. [1] Dipsogenic DI is a result of excessive fluid intake due to damage to the hypothalamic thirst mechanism. [1]
Polydipsia is excessive thirst or excess drinking. [1] The word derives from Greek πολυδίψιος (poludípsios) 'very thirsty', [2] which is derived from Ancient Greek πολύς (polús) 'much, many' and δίψα (dípsa) 'thirst'. Polydipsia is a nonspecific symptom in various medical disorders.
Loss of over 10% of total body water can cause physical and mental deterioration, accompanied by severe thirst. Death occurs with a 15 and 25% loss of body water. [4] Mild dehydration usually resolves with oral rehydration, but severe cases may need intravenous fluids. Dehydration can cause hypernatremia (high levels of sodium ions in the blood).
Homeostatic feeling is a class of feelings (e.g. thirst, fatigue, pain, desire, malaise, well-being) that inform us about our physiological condition. [1] In his earlier work Antonio Damasio used " primordial feeling " but he now prefers the term "homeostatic feeling" for the class.
Central nervous system fatigue is a key component in preventing peripheral muscle injury. [28] The brain has numerous receptors, such as osmoreceptors, to track dehydration, nutrition, and body temperature. With that information as well as peripheral muscle fatigue information, the brain can reduce the quantity of motor commands sent from the ...
Polyphagia is not a disorder by itself; rather, it is a symptom indicating an underlying medical condition. It is frequently a result of abnormal blood glucose levels (both hyperglycemia and hypoglycemia), and, along with polydipsia and polyuria, it is one of the "3 Ps" commonly associated with uncontrolled diabetes mellitus. [2]