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Part of creating a treatment strategy for migraine involves reducing and preventing central sensitization because when that kicks in, "it's harder to treat migraines and certain medications don't ...
If lifestyle changes don’t stop your migraine attacks, there are some over-the-counter (OTC) and prescription medications that may either relieve pain or prevent migraine headaches from ...
Treatment typically focuses on addressing the underlying causes, such as reducing stress or doing physical therapy, but prescription medications may be used if the headaches are frequent, Cohen noted.
Excedrin is a combination medication composed of acetaminophen, aspirin, and caffeine. These medications treat migraine headache in a variety of ways. Acetaminophen is a fever reducer and painkiller. Its precise mechanism is unknown. It is known that it mostly affects the brain and spinal cord, which are parts of the central nervous system.
Atogepant demonstrated efficacy in two phase 3 trials (ADVANCE and PROGRESS) by significantly reducing monthly migraine days, acute medication use, and improving quality of life in patients with episodic and chronic migraine over 12 weeks compared to placebo. [13] Common side effects included nausea, constipation, and fatigue/somnolence.
Rescue treatment involves acute symptomatic control with medication. [4] Recommendations for rescue therapy of migraine include: (1) migraine-specific agents such as triptans, CGRP antagonists, or ditans for patients with severe headaches or for headaches that respond poorly to analgesics, (2) non-oral (typically nasal or injection) route of administration for patients with vomiting, (3) avoid ...
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