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Related: Benadryl for Dogs: Side Effects of Long-Term Use. Signs of Benadryl Overdose in Dogs. At normal doses, Benadryl is quite safe, but a survey of over 600 dogs (1) found the following signs ...
After this has been diagnosed by biopsy and treated with a higher dose of prednisone and oral diphenhydramine (Benadryl is usually used, but your veterinarian may choose to use cetirizine), it ...
Benadryl containing diphenhydramine can interact with alcohol as both are central nervous system (CNS) depressants. Side effects such as drowsiness and dizziness may be enhanced when taking alcohol with diphenhydramine. [16] Mixing diphenhydramine with alcohol can also increase the chances of losing consciousness due to sedation. [17]
The most prominent side effects are dizziness and sleepiness. [41] Diphenhydramine is a potent anticholinergic agent and potential deliriant in higher doses. This activity is responsible for the side effects of dry mouth and throat, increased heart rate, pupil dilation, urinary retention, constipation, and, at high doses, hallucinations or ...
First-generation antihistamines like diphenhydramine and chlorpheniramine are able to move from the blood into the brain across the blood–brain barrier, where they block the H1 receptor, reducing the neurotransmitter effect of histamine, leading to central nervous system side effects such as drowsiness and confusion. [48]
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