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A chemotherapy regimen is a regimen for chemotherapy, defining the drugs to be used, their dosage, the frequency and duration of treatments, and other considerations.In modern oncology, many regimens combine several chemotherapy drugs in combination chemotherapy.
The combination is then referred to as COP (cyclophosphamide, Oncovin, and prednisone or prednisolone) or CVP (cyclophosphamide, vincristine, and prednisone or prednisolone). As elderly patients have a greater risk of toxicity from the drugs, an option is to use an attenuated drug regimen, called miniCHOP.
Prednisone is a synthetic glucocorticoid used for its anti-inflammatory and immunosuppressive properties. [36] [37] Prednisone is a prodrug; it is metabolised in the liver by 11-β-HSD to prednisolone, the active drug. Prednisone has no substantial biological effects until converted via hepatic metabolism to prednisolone. [38]
The incidence of debilitating grades of diarrhea was reduced from 18% in the BSA-dosed group to 4% in the dose-adjusted group and serious hematologic side effects were eliminated. [23] Because of the reduced toxicity, dose-adjusted patients were able to be treated for longer periods of time. [23]
Melanoma, lung cancer, malignant pleural mesothelioma, renal cell carcinoma, Hodgkin lymphoma, head and neck cancer, urothelial carcinoma, colon cancer, esophageal squamous cell carcinoma, liver cancer, gastric cancer, and esophageal or gastroesophageal junction (GEJ) cancer.
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Electrochemotherapy (ECT) is a relatively novel approach in the treatment of cancer, combining the use of electrical pulses with chemotherapy to enhance drug uptake by cancer cells. While predominantly used for the treatment of skin cancers and accessible tumors, its application in prostate cancer remains experimental and is under clinical ...
He’d need to average 182 a week the rest of the way to bypass Chris Johnson’s 15-year-old standard of 2,509 combined rushing and receiving yards. Barkley’s had at least 182 yards four times ...
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