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Polycystic ovary syndrome, or polycystic ovarian syndrome (PCOS), is the most common endocrine disorder in women of reproductive age. [14] The syndrome is named after cysts which form on the ovaries of some women with this condition, though this is not a universal symptom, and not the underlying cause of the disorder.
It plays a central role in the multiple imbalances and dysfunctions of polycystic ovary syndrome. During the first two years after menarche 50% of the menstrual cycles could be anovulatory cycles. It is in fact possible to restore ovulation using appropriate medication, and ovulation is successfully restored in approximately 90% of cases.
Polycystic ovary syndrome is a hormonal condition that can cause a slew of health issues, including unwanted facial hair, acne, irregular periods, weight gain, and infertility. “The improvement ...
Clomiphene is initiated for use in patients with polycystic ovary syndrome, psychogenic amenorrhea, post-oral contraceptive amenorrhea, and secondary amenorrhea of unidentified cause. [14] Serum estrogen should be measured prior to therapy which rules out primary pituitary or ovarian failure, endometrial carcinoma, hyperprolactinaemia. [14]
Clomifene, also known as clomiphene, is a medication used to treat infertility in women who do not ovulate, including those with polycystic ovary syndrome. [5] It is taken by mouth. [5] Common side effects include pelvic pain and hot flashes. [5] Other side effects can include changes in vision, vomiting, trouble sleeping, ovarian cancer, and ...
Flutamide has been researched and used extensively in the treatment of androgen-dependent skin and hair conditions in women including acne, seborrhea, hirsutism, and scalp hair loss, as well as in hyperandrogenism (e.g., in polycystic ovary syndrome or congenital adrenal hyperplasia), and is effective in improving the symptoms of these conditions.
GLP-1 agonists are recommended as a treatment for polycystic ovary syndrome, alone or in combination with metformin. The combination therapy has shown greater efficacy in improving body weight, insulin sensitivity, hyperandrogenism, and menstrual cycle irregularities. [18] This usage is off label. [19]
Though surgery is not commonly performed, the polycystic ovaries can be treated with a laparoscopic procedure called "ovarian drilling" (puncture of 4-10 small follicles with electrocautery), which often results in either resumption of spontaneous ovulations or ovulations after adjuvant treatment with clomiphene or FSH. [14]
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