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  2. Prothrombin G20210A - Wikipedia

    en.wikipedia.org/wiki/Prothrombin_G20210A

    Because prothrombin is also known as factor II, the mutation is also sometimes referred to as the factor II mutation or simply the prothrombin mutation; in either case, the names may appear with or without the accompanying G20210A location specifier (unhelpfully, since prothrombin mutations other than G20210A are known).

  3. Hypoprothrombinemia - Wikipedia

    en.wikipedia.org/wiki/Hypoprothrombinemia

    A mutation in factor II would essentially lead to hypoprothrombinemia. The mutation is presented on chromosome 11. [9] Areas where the disease has been shown to present itself at include the liver, since the glycoprotein is stored in this area. Acquired cases are results from an isolated factor II deficiency. Specific cases include:

  4. Thrombin - Wikipedia

    en.wikipedia.org/wiki/Thrombin

    Thrombin (Factor IIa) (EC 3.4.21.5, fibrose, thrombase, thrombofort, topical, thrombin-C, tropostasin, activated blood-coagulation factor II, E thrombin, beta-thrombin, gamma-thrombin) is a serine protease, that converts fibrinogen into strands of insoluble fibrin, as well as catalyzing many other coagulation-related reactions.

  5. Prothrombinase - Wikipedia

    en.wikipedia.org/wiki/Prothrombinase

    The prothrombinase complex catalyzes the conversion of prothrombin (factor II), an inactive zymogen, to thrombin (factor IIa), an active serine protease. The activation of thrombin is a critical reaction in the coagulation cascade , which functions to regulate hemostasis in the body.

  6. Thrombophilia - Wikipedia

    en.wikipedia.org/wiki/Thrombophilia

    They are relatively mild in the usual heterozygous state, and are therefore classified as "type II" defects. [14] [15] The most common ones are factor V Leiden (a mutation in the F5 gene at position 1691) and prothrombin G20210A, a mutation in prothrombin (at position 20210 in the 3' untranslated region of the gene).

  7. Is It Just Stress...Or Perimenopause? Doctors Explain ... - AOL

    www.aol.com/just-stress-perimenopause-doctors...

    Here's how to pinpoint when you're actually in this phase of life even if your symptoms (hot flashes, mood swings, stress, dryness) are nonspecific.

  8. Prothrombin fragment 1+2 - Wikipedia

    en.wikipedia.org/wiki/Prothrombin_fragment_1+2

    Prothrombin fragment 1+2 (F1+2), also written as prothrombin fragment 1.2 (F1.2), is a polypeptide fragment of prothrombin (factor II) generated by the in vivo cleavage of prothrombin into thrombin (factor IIa) by the enzyme prothrombinase (a complex of factor Xa and factor Va). [1] [2] [3] It is released from the N-terminus of prothrombin. [3]

  9. Moral Injury: The Grunts - The Huffington Post

    projects.huffingtonpost.com/moral-injury/the...

    Can we imagine ourselves back on that awful day in the summer of 2010, in the hot firefight that went on for nine hours? Men frenzied with exhaustion and reckless exuberance, eyes and throats burning from dust and smoke, in a battle that erupted after Taliban insurgents castrated a young boy in the village, knowing his family would summon nearby Marines for help and the Marines would come ...