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Intravenous sugar solution, also known as dextrose solution, is a mixture of dextrose (glucose) and water. [1] It is used to treat low blood sugar or water loss without electrolyte loss. [ 2 ] Water loss without electrolyte loss may occur in fever , hyperthyroidism , high blood calcium , or diabetes insipidus . [ 2 ]
The most commonly used crystalloid fluid is normal saline, a solution of sodium chloride at 0.9% concentration, which is close to the concentration in the blood . [3] Ringer's lactate or Ringer's acetate is another isotonic solution often used for large-volume fluid replacement.
A hypertonic solution has a greater concentration of non-permeating solutes than another solution. [2] In biology, the tonicity of a solution usually refers to its solute concentration relative to that of another solution on the opposite side of a cell membrane ; a solution outside of a cell is called hypertonic if it has a greater ...
The science of fluid balance across fluid compartments has practical application in intravenous therapy, where doctors and nurses must predict fluid shifts and decide which IV fluids to give (for example, isotonic versus hypotonic), how much to give, and how fast (volume or mass per minute or hour).
For example: glucose has n of 1, while NaCl has n of 2; C is the molar concentration of the solute; the index i represents the identity of a particular solute. Osmolarity can be measured using an osmometer which measures colligative properties, such as Freezing-point depression, Vapor pressure, or Boiling-point elevation.
However, tonicity does not have to relate to a cell. For example, a hypertonic solution is simply one with a greater impermeable solute concentration than the solution to which it is being compared. You can separate any two fluids with a semi-permeable membrane and have one be hyper/hypo/isotonic to the other.
"The Hydrating Effects of Hypertonic, Isotonic and Hypotonic Sports Drinks and Waters on Central Hydration During Continuous Exercise: A Systematic Meta-Analysis and Perspective." Sports Medicine ...
Osmoregulation is the active regulation of the osmotic pressure of an organism's body fluids, detected by osmoreceptors, to maintain the homeostasis of the organism's water content; that is, it maintains the fluid balance and the concentration of electrolytes (salts in solution which in this case is represented by body fluid) to keep the body fluids from becoming too diluted or concentrated.