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In Ohio, the highway runs 194.27 miles (312.65 km) from the Ohio River in Cincinnati to the Michigan state line north of West Unity. US 127 runs south to north in Ohio's westernmost counties along the border of Indiana. The highway is a main route connecting many small towns, including eight county seats. The highway was first designated in 1926.
State Route 450 (SR 450) is a short east–west state highway in southwestern Ohio, specifically near the eastern Cincinnati suburb of Milford.The western terminus of State Route 450 is at the Milford city limits, just west of a partial cloverleaf interchange with Interstate 275, with the road continuing into Milford known as Milford Parkway, which passes by the River's Edge Shopping Center ...
The road has an at-grade crossing with former Big Four branch line railroad track, before curving southeast. US 50 has a traffic signal at the intersection with SR 128. Southeast of SR 128, US 50 becomes a four-lane divided highway and crosses over the Great Miami River.
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US 27 enters Ohio on the Taylor–Southgate Bridge over the Ohio River as a four-lane highway. After the bridge ends, the highway makes a loop to the east around a parking structure on Pete Rose and Mehring ways, concurrent with US 52. Mehring Way curves towards the west and passes under the Taylor–Southgate Bridge.
Southbound exit only to Neff Road; indirect southbound exit to Wagner Ford Road via Keats Drive; indirect access to Siebenthaler Avenue in both directions via Wagner Ford Road and Dixie Drive; was exit 57B before Neva Drive exit was removed: Northridge–Harrison Township line: 58.21: 93.68: 45: 58: Needmore Road: Vandalia–Butler Township ...
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