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Antipsychotics by class Generic name Brand names Chemical class ATC code Typical antipsychotics; Acepromazine: Atravet, Acezine: phenothiazine: N05AA04
The atypical antipsychotics (AAP), also known as second generation antipsychotics (SGAs) and serotonin–dopamine antagonists (SDAs), [1] [2] are a group of antipsychotic drugs (antipsychotic drugs in general are also known as tranquilizers and neuroleptics, although the latter is usually reserved for the typical antipsychotics) largely introduced after the 1970s and used to treat psychiatric ...
Ziprasidone (and all other second generation antipsychotics (SGAs)) received a black box warning due to increased mortality in elderly patients with dementia-related psychosis. [14] Sleepiness and headache are very common adverse effects (>10%). [6] [7]
Cariprazine, sold under the brand name Vraylar among others, is an atypical antipsychotic developed by Gedeon Richter, [8] which is used in the treatment of schizophrenia, bipolar mania, [9] bipolar depression, [10] and major depressive disorder. [6] It acts primarily as a D 3 and D 2 receptor partial agonist, with a preference for the D 3 ...
Antipsychotics work best in the manic phase of bipolar disorder. [20] Second-generation or atypical antipsychotics (including aripiprazole , olanzapine , quetiapine , paliperidone , risperidone , and ziprasidone ) have emerged as effective mood stabilizers. [ 2 ]
Second-generation (atypical) antipsychotics: The concept of "atypicality" is from the finding that second generation antipsychotics (SGAs) have a greater serotonin/dopamine ratio than earlier drugs, and might be associated with improved efficacy (particularly for the negative symptoms of psychosis) and reduced extrapyramidal side effects.
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Tiotixene, or thiothixene is a typical antipsychotic agent currently sold under the brand name Navane which is predominantly utilised to treat acute and chronic schizophrenia. [2] Beyond its primary indication , it can exhibit a variety of effects common to neuroleptic drugs including anxiolytic , anti-depressive, and anti-aggressive properties.