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Compared to placebo, risperidone treatment reduces certain problematic behaviors in autistic children, including aggression toward others, self-injury, challenging behavior, and rapid mood changes. [31] The evidence for its efficacy appears to be greater than that for alternative pharmacological treatments. [32]
Research programme: autism and obesity therapeutics - Berand Neuropharmacology – histone deacetylase inhibitors [61] Research programme: brain development disorder therapeutics - Seaside Therapeutics (STX-110) – metabotropic glutamate mGlu 5 receptor antagonists and muscarinic acetylcholine M 1 receptor antagonists [62]
The FDA's decision was based in part on a study of autistic children with severe and enduring problems of tantrums, aggression, and self-injury; risperidone is not recommended for autistic children with mild aggression and explosive behavior without an enduring pattern. [122]
Rash (oral, adults, 1% to 4%; pediatrics, up to 11% ; IM, less than 4%) Hyperprolactinaemia (risperidone is probably the most notorious antipsychotic for causing hyperprolactinaemia via its potent blockade of D2 receptors expressed on the lactotrophic cells of the pituitary) [5] (oral, adults, less than 1%; pediatrics, 49% to 87% ; IM, less ...
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A survey of children with pervasive developmental disorder found that 16.5% were taking an antipsychotic drug, most commonly for irritability, aggression, and agitation. Both risperidone and aripiprazole have been approved by the US FDA for the treatment of irritability in autistic children and adolescents. [85]
How common is it to be diagnosed with autism as an adult? An estimated 5.4 million (or 2.21%) of adults in the U.S. have autism spectrum disorder, according to the Centers for Disease Control and ...
Autism in Adulthood is a quarterly peer-reviewed academic journal covering research across a range of disciplines on all aspects of autism spectrum disorders in adults. It was established in 2019 and is published by Mary Ann Liebert. The founding editor-in-chief is Christina Nicolaidis (Portland State University). [1]
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