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Lymphadenopathy or adenopathy is a disease of the lymph nodes, in which they are abnormal in size or consistency. Lymphadenopathy of an inflammatory type (the most common type) is lymphadenitis , [ 1 ] producing swollen or enlarged lymph nodes.
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The term lymphadenopathy strictly speaking refers to disease of the lymph nodes, [1] though it is often used to describe the enlargement of the lymph nodes. Similarly, the term lymphadenitis refers to inflammation of a lymph node, but often it is used as a synonym of lymphadenopathy. Cervical lymphadenopathy is a sign or a symptom, not a diagnosis.
In mammals, including humans, the lymphatic system is composed of a network of thin vessels that branch, like blood vessels, into tissues throughout the body.Lymphatic vessels carry lymph, a colorless, watery fluid originating from interstitial fluid (fluid in the tissues) which is squeezed out of the blood vessels.
Follicular hyperplasia (FH) is a type of lymphoid hyperplasia and is classified as a lymphadenopathy, which means a disease of the lymph nodes.It is caused by a stimulation of the B cell compartment and by abnormal cell growth of secondary follicles.
Lymph node enlargement or swelling is known as lymphadenopathy. [27] Swelling may be due to many causes, including infections , tumors , autoimmune disease , drug reactions , diseases such as amyloidosis and sarcoidosis , or because of lymphoma or leukemia .
The signs and symptoms of Kikuchi disease are fever, enlargement of the lymph nodes (lymphadenopathy), skin rashes, and headache. [7] In sixty to ninety percent of cases, lymphadenopathy presents in the posterior cervical lymph nodes with diameter enlargement typically being between one and two centimeters, but up to seven centimeters has been reported in literature.
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