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Thin endometrium may be defined as an endometrial thickness of less than 8 mm. It usually occurs after menopause. Treatments that can improve endometrial thickness include Vitamin E, L-arginine and sildenafil citrate. [17] Gene expression profiling using cDNA microarray can be used for the diagnosis of endometrial disorders. [18]
Taking a progestogen in addition to an estrogen patch should be considered for women who have not undergone a hysterectomy to regulate the thickness of the endometrial lining [2] and reduce the risk of endometrial cancer. Hysterectomized women rarely need a progestogen, however it may be considered if a history of endometriosis exists. [1]
Estrogens may be used in treatment of infertility in women when there is a need to develop sperm-friendly cervical mucus or an appropriate uterine lining. [65] [66] It is also commonly used during in vitro fertilization (IVF). Estrogen helps maintain the endometrial lining of the uterus and help prepare for pregnancy.
Nice stressed that the symptoms women experience are real and treatments are available. Women with menopause symptoms ‘should be offered HRT as first-line treatment’ Skip to main content
Endometrial polyps are usually benign although some may be precancerous or cancerous. [3] About 0.5% of endometrial polyps contain adenocarcinoma cells. [14] Polyps can increase the risk of miscarriage in women undergoing IVF treatment. [3] If they develop near the fallopian tubes, they may lead to difficulty in becoming pregnant. [3]
Androgens do not stimulate endometrial proliferation in post menopausal women, and appear to inhibit the proliferation induced by estrogen to a certain extent. [55] There is insufficient high‐quality evidence to inform women considering hormone replacement therapy after treatment for endometrial cancer. [56]
The finding on transvaginal ultrasound of a thin endometrial lining gives the physician a 99% negative predictive value that the patient does not have endometrial cancer. [3] If a patient had a prior endometrial sampling that was inconclusive, then a transvaginal ultrasound can be used to triage a woman with post-menopausal bleeding. [3]
Endometrial cancer (cancer of the uterine lining) — bleeding can also be irregular, in between periods, or after the menopause (post-menopausal bleeding or PMB) Endometrial polyp; Painful (i.e. associated with dysmenorrhea): Pelvic inflammatory disease; Adenomyosis - extension of the endometrial tissue into the outer muscular wall of the ...
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