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Adderall and Mydayis [11] are trade names [note 2] for a combination drug containing four salts of amphetamine.The mixture is composed of equal parts racemic amphetamine and dextroamphetamine, which produces a (3:1) ratio between dextroamphetamine and levoamphetamine, the two enantiomers of amphetamine. [13]
The drugs include Adderall, Vyvanse and generic amphetamines, such as dextroamphetamine. The link between amphetamines and psychosis isn’t new. Amphetamines increase levels of dopamine in the brain.
In rodents and primates, sufficiently high doses of amphetamine cause dopaminergic neurotoxicity, or damage to dopamine neurons, which is characterized by dopamine terminal degeneration and reduced transporter and receptor function. [169] [170] There is no evidence that amphetamine is directly neurotoxic in humans.
[46] [51] [53] Lisdexamfetamine is an inactive prodrug of dextroamphetamine (i.e., lisdexamfetamine itself does not do anything in the body, but it metabolizes into dextroamphetamine). [46] Adderall is a proprietary mixture of (75%) dextroamphetamine and (25%) levoamphetamine salts, which results in very mild differences between their effects. [46]
Plus, there’s the question of addiction: If you stop taking stimulant medications (like Adderall) quickly after a period of chronic misuse or overuse, you may experience withdrawal symptoms.
A dopamine reuptake inhibitor (DRI) is a class of drug which acts as a reuptake inhibitor of the monoamine neurotransmitter dopamine by blocking the action of the dopamine transporter (DAT). Reuptake inhibition is achieved when extracellular dopamine not absorbed by the postsynaptic neuron is blocked from re-entering the presynaptic neuron.
Adderall and Ritalin, the study drugs of choice in universities around the country, will let you write a physics paper from sundown to sunup. First synthesized in the 1940s to treat fatigue ...
It was previously marketed by itself under the brand name Cydril, but is now available only in combination with dextroamphetamine in varying ratios under brand names like Adderall and Evekeo. [ 10 ] [ 5 ] The drug is known to increase wakefulness and concentration in association with decreased appetite and fatigue .
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