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Sep. 1—(Family Features) In a healthy person, the body is like a well-oiled machine. However, sometimes things go wrong, and when that happens, finding the source of damage, illness or disease ...
The free radical theory of aging states that organisms age because cells accumulate free radical damage over time. [ 1 ] A free radical is any atom or molecule that has a single unpaired electron in an outer shell. [ 2 ] While a few free radicals such as melanin are not chemically reactive, most biologically relevant free radicals are highly ...
Ionization of molecules can lead to radiolysis (breaking chemical bonds), and formation of highly reactive free radicals. These free radicals may then react chemically with neighbouring materials even after the original radiation has stopped. (e.g., ozone cracking of polymers by ozone formed by ionization of air). Ionizing radiation can also ...
Glutathione is capable of preventing damage to important cellular components caused by sources such as reactive oxygen species, free radicals, peroxides, lipid peroxides, and heavy metals. [2] It is a tripeptide with a gamma peptide linkage between the carboxyl group of the glutamate side chain and cysteine .
Free radicals have an ominous name and a lot of people misunderstand them, their complex role in our bodies and how to manage them. Free radicals have an ominous name and a lot of people ...
Oxidative stress mechanisms in tissue injury. Free radical toxicity induced by xenobiotics and the subsequent detoxification by cellular enzymes (termination).. Oxidative stress reflects an imbalance between the systemic manifestation of reactive oxygen species and a biological system's ability to readily detoxify the reactive intermediates or to repair the resulting damage. [1]
Lipid peroxidation, or lipid oxidation, is a complex chemical process that leads to oxidative degradation of lipids, [1] resulting in the formation of peroxide and hydroperoxide derivatives. [2] It occurs when free radicals, specifically reactive oxygen species (ROS), interact with lipids within cell membranes, typically polyunsaturated fatty ...
In chemistry and biology, reactive oxygen species (ROS) are highly reactive chemicals formed from diatomic oxygen (O2), water, and hydrogen peroxide. Some prominent ROS are hydroperoxide (O 2 H), superoxide (O 2-), [ 1 ] hydroxyl radical (OH.), and singlet oxygen. [ 2 ] ROS are pervasive because they are readily produced from O 2, which is ...