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  2. Clostridioides difficile infection - Wikipedia

    en.wikipedia.org/wiki/Clostridioides_difficile...

    Signs and symptoms of CDI range from mild diarrhea to severe life-threatening inflammation of the colon. [16]In adults, a clinical prediction rule found the best signs to be significant diarrhea ("new onset of more than three partially formed or watery stools per 24-hour period"), recent antibiotic exposure, abdominal pain, fever (up to 40.5 °C or 105 °F), and a distinctive foul odor to the ...

  3. Clostridioides difficile - Wikipedia

    en.wikipedia.org/wiki/Clostridioides_difficile

    The incubation period is 5–10 days, with a range of 1 day to weeks following antibiotic treatment for antibiotic associated diarrhea. Additionally, carriage of C. difficile with high levels of toxins is common in young children, while disease is rare. The production of one or even both toxins is not always sufficient for producing symptoms.

  4. List of antibiotic-resistant bacteria - Wikipedia

    en.wikipedia.org/wiki/List_of_antibiotic...

    The evolution of bacteria on a "Mega-Plate" petri dish A list of antibiotic resistant bacteria is provided below. These bacteria have shown antibiotic resistance (or antimicrobial resistance). Gram positive Clostridioides difficile Clostridioides difficile is a nosocomial pathogen that causes diarrheal disease worldwide. Diarrhea caused by C. difficile can be life-threatening. Infections are ...

  5. Tolevamer - Wikipedia

    en.wikipedia.org/wiki/Tolevamer

    Tolevamer was designed to bind the enterotoxins of Clostridioides difficile. Since it has no antibiotic properties, it does not harm the gut flora. Early studies used the sodium salt, but it was soon replaced with the potassium sodium salt to prevent hypokalaemia, which is often associated with diarrhea. [2] [3]

  6. Fecal microbiota transplant - Wikipedia

    en.wikipedia.org/wiki/Fecal_microbiota_transplant

    Scanning electron micrograph of Clostridioides difficile bacteria from a stool sample. Fecal microbiota transplant is approximately 85–90% effective in people with CDI for whom antibiotics have not worked or in whom the disease recurs following antibiotics. [12] [13] Most people with CDI recover with one FMT treatment. [8] [14] [15]

  7. Antibiotic-associated diarrhea - Wikipedia

    en.wikipedia.org/wiki/Antibiotic-associated_diarrhea

    Clostridioides difficile, also known more commonly as C. diff, accounts for 10 to 20% of antibiotic-associated diarrhea cases, because the antibiotics administered for the treatment of certain disease processes such as inflammatory colitis also inadvertently kill a large portion of the gut flora, the normal flora that is usually present within the bowel.

  8. Metronidazole - Wikipedia

    en.wikipedia.org/wiki/Metronidazole

    It is used either alone or with other antibiotics to treat pelvic inflammatory disease, endocarditis, and bacterial vaginosis. [10] It is effective for dracunculiasis, giardiasis, trichomoniasis, and amebiasis. [10] It is an option for a first episode of mild-to-moderate Clostridioides difficile colitis if vancomycin or fidaxomicin is unavailable.

  9. Fidaxomicin - Wikipedia

    en.wikipedia.org/wiki/Fidaxomicin

    It is used for the treatment of Clostridioides difficile infection, which is also known as Clostridioides difficile-associated diarrhea or Clostridioides difficile-associated illness (CDI), and can develop into Clostridioides difficile colitis and pseudomembranous colitis. It is approved as a generic medication. [8]

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