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  2. Lilly, Boehringer say Jardiance slows kidney disease ... - AOL

    www.aol.com/news/lilly-boehringer-jardiance...

    In a statement on Friday, the two partners said Jardiance cut the risk of kidney disease progression and cardiovascular death by 28%, citing results from a late-stage trial which included people ...

  3. Empagliflozin - Wikipedia

    en.wikipedia.org/wiki/Empagliflozin

    Empagliflozin sometimes causes a transient decline in kidney function, and on rare occasions causes acute kidney injury, so use should be monitored in those with kidney dysfunction. But some trials have indicated that empagliflozin can be used in people with an eGFR as low as 20 mL/min/1.73 m², without increasing adverse kidney outcomes. [17] [18]

  4. SGLT2 inhibitor - Wikipedia

    en.wikipedia.org/wiki/SGLT2_inhibitor

    SGLT2 is mainly expressed in the kidneys on the epithelial cells lining the first segment of the proximal convoluted tubule. By inhibiting SGLT2, gliflozins prevent the kidneys' reuptake of glucose from the glomerular filtrate and subsequently lower the glucose level in the blood and promote the excretion of glucose in the urine . [41] [42]

  5. Eli Lilly, Boehringer Share Jardiance Data In Heart ... - AOL

    www.aol.com/news/eli-lilly-boehringer-share...

    In the trial, Jardiance cut the combined risk of cardiovascular death or hospitalization from heart failure in HFpEF patients with or without diabetes. At the 26-month mark, 13.8% of Jardiance ...

  6. Rhabdomyolysis - Wikipedia

    en.wikipedia.org/wiki/Rhabdomyolysis

    In addition to the myoglobinuria, two other mechanisms contribute to kidney impairment: low blood pressure leads to constriction of the blood vessels and therefore a relative lack of blood flow to the kidney, and finally uric acid may form crystals in the tubules of the kidneys, causing obstruction.

  7. Study links e-cigarettes to incurable disease called 'Popcorn ...

    www.aol.com/news/study-links-e-cigarettes...

    Popcorn Lung is a debilitating and irreversible respiratory disease which causes "scarring in tiny air sacs in the lungs that lead to excessive coughing and shortness of breath" similar to that ...

  8. Kidney failure - Wikipedia

    en.wikipedia.org/wiki/Kidney_failure

    Failure of kidneys to remove excess fluid may cause: Swelling of the hands, legs, ankles, feet, or face; Shortness of breath due to extra fluid on the lungs (may also be caused by anemia) Polycystic kidney disease, which causes large, fluid-filled cysts on the kidneys and sometimes the liver, can cause: Pain in the back or side

  9. Pulmonary contusion - Wikipedia

    en.wikipedia.org/wiki/Pulmonary_contusion

    People with pulmonary contusion who are especially likely to need ventilation include those with prior severe lung disease or kidney problems; the elderly; those with a lowered level of consciousness; those with low blood oxygen or high carbon dioxide levels; and those who will undergo operations with anesthesia. [41]

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