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Bruce Nathan Ames (December 16, 1928 – October 5, 2024) was an American biochemist who was a professor of biochemistry and Molecular Biology Emeritus at the University of California, Berkeley, and was a senior scientist at Children's Hospital Oakland Research Institute (CHORI). [2]
Nitroglycerin is an example that gives a positive Ames yet is still used in treatment today. Nitrates in food however may be reduced by bacterial action to nitrites which are known to generate carcinogens by reacting with amines and amides. Long toxicology and outcome studies are needed with such compounds to disprove a positive Ames test.
An article by Bruce Ames in The Proceedings of the National Academy of Sciences in 2018 identified pyrroloquinoline quinone as a "longevity vitamin" not essential for immediate survival, but necessary for long-term health. [14]
The basic nature of cancer cells, the role of viral and chemical carcinogens, and a relationship of cancer to genes, are described. Several successful cancer therapies are examined. The 1950 Wynder and Graham Study is reviewed. The research of Bradford Hill and Richard Doll is covered with respect to chemical carcinogenesis. Bruce Ames zeros in ...
The analysis, published in the journal Frontiers in Toxicology, builds upon research published earlier this year, which identified more than 900 chemicals as being potential mammory carcinogens ...
Highly Toxic: a gas that has a LC 50 in air of 200 ppm or less. [2] NFPA 704: Materials that, under emergency conditions, can cause serious or permanent injury are given a Health Hazard rating of 3. Their acute inhalation toxicity corresponds to those vapors or gases having LC 50 values greater than 1,000 ppm but less than or equal to 3,000 ppm ...
The World Health Organization has identified glyphosate as "possibly carcinogenic to humans" and a study published earlier this year showed that glyphosate raised the cancer risk of those exposed ...
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