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Meconium aspiration syndrome (MAS), also known as neonatal aspiration of meconium, is a medical condition affecting newborn infants. It describes the spectrum of disorders and pathophysiology of newborns born in meconium-stained amniotic fluid (MSAF) and have meconium within their lungs. Therefore, MAS has a wide range of severity depending on ...
Inhaled nitric oxide is a gas that is inhaled. [1] It was initially described in 1987 as an "endothelial-derived relaxing factor" and has since been used to treat pulmonary disorders. [3] It works by relaxing smooth muscle to widen (dilate) blood vessels, especially in the lungs. [1] Inhaled nitric oxide selects only pulmonary smooth muscles.
These look after the smallest, most premature and most unwell babies and often serve a large geographical region. Therapies such as prolonged mechanical ventilation, therapeutic hypothermia, neonatal surgery and inhaled nitric oxide are usually provided in Level 3 Units, although not every unit has access to all therapies. Some babies being ...
Specifically, Dr. Ballard studies ways to treat and prevent chronic lung disease in premature infants. Some of her research includes the collection of data regarding how inhaled Nitric Oxide can help premature infants who are suffering from lung disease and are undergoing medical ventilation.
Pulmonary vasodilators like sildenafil or inhaled nitric oxide can be used to reduce pulmonary blood pressures. [6] For those with severe ACD, these measures offer only momentary improvement. As symptoms worsen, ECMO can be used, but it also offers only brief improvement. There are no effective treatments for severe ACD. [1]
Nitric oxide is absorbed systemically after inhalation. Most of it moves across the pulmonary capillary bed where it combines with hemoglobin that is 60% to 100% oxygen-saturated. Nitrate has been identified as the predominant nitric oxide metabolite excreted in the urine, accounting for >70% of the nitric oxide dose inhaled.
They may be involved in emergency care like inserting and managing an airway, humidification of oxygen, administering diagnostic lung mechanics tests, invasive or non-invasive mechanical ventilation management, weaning the ventilator, aerosol therapy (pulmonary vasodilatory medications included), inhaled Nitric oxide therapy, arterial blood gas ...
The Life Pulse High Frequency Jet Ventilator Bidirectional Flow During HFJV Inhaled nitric oxide (iNO) delivery with high-frequency jet ventilation. HFJV is provided by the Bunnell Life Pulse High-Frequency Ventilator. HFJV employs an endotracheal tube adaptor in place for the normal 15 mm ET tube adaptor.