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  2. Polyadenylation - Wikipedia

    en.wikipedia.org/wiki/Polyadenylation

    The RNA is typically cleaved before transcription termination, as CstF also binds to RNA polymerase II. [28] Through a poorly understood mechanism (as of 2002), it signals for RNA polymerase II to slip off of the transcript. [29] Cleavage also involves the protein CFII, though it is unknown how. [30]

  3. Termination signal - Wikipedia

    en.wikipedia.org/wiki/Termination_signal

    Overview of transcription process. Termination of transcription occurs due to termination signal. In molecular biology, a termination signal is a sequence that signals the end of transcription or translation. [1] Termination signals are found at the end of the part of the chromosome being transcribed during transcription of mRNA.

  4. Transcription (biology) - Wikipedia

    en.wikipedia.org/wiki/Transcription_(biology)

    Transcription termination in eukaryotes is less well understood than in bacteria, but involves cleavage of the new transcript followed by template-independent addition of adenines at its new 3' end, in a process called polyadenylation. [49]

  5. Terminator (genetics) - Wikipedia

    en.wikipedia.org/wiki/Terminator_(genetics)

    In genetics, a transcription terminator is a section of nucleic acid sequence that marks the end of a gene or operon in genomic DNA during transcription.This sequence mediates transcriptional termination by providing signals in the newly synthesized transcript RNA that trigger processes which release the transcript RNA from the transcriptional complex.

  6. Post-transcriptional modification - Wikipedia

    en.wikipedia.org/wiki/Post-transcriptional...

    The pre-mRNA processing at the 3' end of the RNA molecule involves cleavage of its 3' end and then the addition of about 250 adenine residues to form a poly(A) tail.The cleavage and adenylation reactions occur primarily if a polyadenylation signal sequence (5'- AAUAAA-3') is located near the 3' end of the pre-mRNA molecule, which is followed by another sequence, which is usually (5'-CA-3') and ...

  7. Three prime untranslated region - Wikipedia

    en.wikipedia.org/wiki/Three_prime_untranslated...

    In molecular genetics, the three prime untranslated region (3′-UTR) is the section of messenger RNA (mRNA) that immediately follows the translation termination codon. The 3′-UTR often contains regulatory regions that post-transcriptionally influence gene expression.

  8. Post-transcriptional regulation - Wikipedia

    en.wikipedia.org/wiki/Post-transcriptional...

    After being produced, the stability and distribution of the different transcripts is regulated (post-transcriptional regulation) by means of RNA binding protein (RBP) that control the various steps and rates controlling events such as alternative splicing, nuclear degradation (), processing, nuclear export (three alternative pathways), sequestration in P-bodies for storage or degradation and ...

  9. Adenine - Wikipedia

    en.wikipedia.org/wiki/Adenine

    Adenine (/ ˈ æ d ɪ n iː n /, / ˈ æ d ɪ n ɪ n /) (symbol A or Ade) is a purine nucleotide base. It is one of the nucleobases in the nucleic acids, DNA and RNA. The shape of adenine is complementary to either thymine in DNA or uracil in RNA. In cells adenine, as an independent molecule, is rare.