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Methotrexate-induced papular eruption appears in patients being treated with methotrexate, such as those with rheumatic disease, presenting with erythematous indurated papules, usually located on the proximal extremities. [1] It has been suggested that it may represent a cutaneous small-vessel vasculitis. [2]
Palindromic rheumatism is a disease of unknown cause. It has been suggested that it is an abortive form of rheumatoid arthritis (RA), since anti-cyclic citrullinated peptide antibodies (anti-CCP) and antikeratin antibodies (AKA) are present in a high proportion of patients, as is the case in rheumatoid arthritis. [6]
A non-blanching rash (NBR) is a skin rash that does not fade when pressed with, and viewed through, a glass. It is a characteristic of both purpuric and petechial rashes. [ 1 ] Individual purpura measure 3–10 mm (0.3–1 cm, 3 ⁄ 32 - 3 ⁄ 8 in), whereas petechiae measure less than 3 mm. [ 2 ]
Chemotherapy-induced acral erythema, also known as palmar-plantar erythrodysesthesia or hand-foot syndrome is reddening, swelling, numbness and desquamation (skin sloughing or peeling) on palms of the hands and soles of the feet (and, occasionally, on the knees, elbows, and elsewhere) that can occur after chemotherapy in patients with cancer.
Although it may occur in the absence of other known disease, SS is often associated with hematologic disease (including leukemia, most commonly acute myelogenous leukemia), solid cancers (especially genitourinary, gastrointestinal and breast cancer) and immunologic diseases including rheumatoid arthritis, and inflammatory bowel disease, Behçet ...
If the rash doesn’t go away after three or four days, if it gets worse, or if a fever develops, call your doctor. They may prescribe medication to help, Katta said. Show comments.
[71] [44] [25] Methotrexate has been observed to be useful in more severe cases. [72] If methotrexate is contraindicated, alternative disease-modifying medications for RA, such as leflunomide or azathioprine, may be used. [68] High dosages of corticosteroids are typically effective in treating acute severe myositis. [44] [73]
"The right pair of shoes can help strengthen your foot's intrinsic (support) muscles as well as allow normal mobility and range of motion in the toes, foot and ankle," says Dr. Milica McDowell ...