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The choice of therapy of SIADH is dependent upon a number of factors including the degree of hyponatremia, the presence or absence of symptoms, the likelihood that the cause of SIADH is reversible, and to some degree, the urine osmolality.
SIADH should be treated to cure symptoms. While this is undisputed in the presence of grave or advanced symptoms, the clinical role and the indications for treatment in the presence of mild to moderate symptoms are currently unclear.
Urgent treatment is required for patients with SIAD who have severe symptoms of hyponatremia (e.g., somnolence, seizures, cardiorespiratory distress, or coma); moderately severe symptoms (e.g ...
First-line treatment of the syndrome of inappropriate antidiuresis (SIAD [the preferred current term instead of the previous term, syndrome of inappropriate secretion of antidiuretic hormone, SIADH]) is fluid restriction followed by increasing solute intake (urea or sodium chloride and low-dose loop diuretics).
SIADH treatment involves correction and maintenance of corrected sodium levels and correction of underlying abnormalities such as hypothyroidism or pulmonary or CNS infection. The goal of sodium correction is more than 130 mEq/L.
The treatment for hyponatremia is chosen on the basis of duration and symptoms. For acute or severely symptomatic hyponatremia, both guidelines adopted the approach of giving a bolus of hypertonic saline.
This topic provides an overview of the treatment of adults with hyponatremia, including the pretreatment evaluation, selection of initial and subsequent therapy, goals of therapy, and common pitfalls.
Treatment is based on symptoms and underlying causes. In general, hyponatremia is treated with fluid restriction (in the setting of euvolemia), isotonic saline (in hypovolemia), and...
This guideline deals with diagnostic tools for impro- ving accuracy of the differential diagnosis of hypo- tonic hyponatraemia, allowing more speciļ¬c treatment
Hypovolemic hyponatremia is treated with normal saline infusions. Treating euvolemic hyponatremia includes restricting free water consumption or using salt tablets or intravenous vaptans....