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Keratitis is an ocular emergency and remains one of the major causes of blindness around the world. Main risk factors include corneal trauma, contact lens wear, and breakdown of the corneal epithelium. The diagnosis depends on a careful history, slit-lamp examination, and corneal scraping cultures. Treatment consists of topical antimicrobial ...
Keratitis is an ocular emergency and remains one of the major causes of blindness around the world. Main risk factors include corneal trauma, contact lens wear, and breakdown of the corneal epithelium. The diagnosis depends on a careful history, slit-lamp examination, and corneal scraping cultures. Treatment consists of topical antimicrobial ...
The keratitis usually improves with low-dose topical corticosteroids (0.12% prednisone or equivalent 2 to 3 times per day for a few days up to 2 weeks as recommended by Arffa, p. 323. Leibowitz et al., recommend that acute episodes be treated aggressively with topical steroids and then tapered and discontinued over a 3 to 4 week interval.)
HSV stromal keratitis is associated with the highest and most severe morbidity of any ocular herpetic disease.[1-4] Although this condition frequently follows previous HSV epithelial keratitis, it can be the initial presentation of ocular herpetic disease. The vast majority of cases are an immune stromal keratitis (ISK), which involves the ...
Photographer: Brice Critser, CRA. Herpetic disciform keratitis is a primary endotheliitis resulting in both stromal and epithelial edema in a round (disciform) distribution with keratic precipitates underlying the area of edema. The corneal edema and keratic precipitates appear to be out of proportion to the degree of anterior chamber ...
Acanthamoeba keratitis is a rare parasitic infection of the cornea that primarily occurs in contact lens wearers. The infection may be limited to the epithelium in its early stages, resulting in epithelial dendrites and punctate epitheliopathy. Later stromal involvement classically results in a partial or complete paracentral ring infiltrate ...
Staphylococcal Marginal Keratitis/Ulcer. Peripheral curvilinear infiltrates in superficial cornea often where the lids cross the corneal periphery associated with loss of corneal epithelium; ulcerations in the marginal zone separated from the limbus by a clear corneal zone. Often associated with blepharitis.
Peripheral ulcerative keratitis (PUK) is an inflammatory corneal condition estimated to affect 3 persons per million per year (1). It predominantly affects older individuals and does not have a significant gender predilection (2,3,4). The condition may be triggered by surgical or non-surgical trauma, or may arise spontaneously (3).
Pseudomonas keratitis is treated with intensive topical antibiotic therapy with fluoroquinolones or fortified Gram-negative antibiotics, including aminoglycosides (e.g., tobramycin), cephalosporins (e.g., ceftazidime), and synthetic penicillins (e.g., carbenicillin). The microbiological response is usually rapid, with stabilization of the ...
Photographer: Cindy Montague, CRA. Varicella-zoster virus (VZV) is a Herpes virus responsible for chicken pox and shingles. With corneal epithelial involvement, the virus can cause punctate or dendritic epithelial keratitis. The pseudodendrites caused by VZV can be differentiated clinically from "true" dendrites caused by Herpes simplex virus ...