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Whilst the muscularis externa is similar throughout the entire gastrointestinal tract, an exception is the stomach which has an additional inner oblique muscular layer to aid with grinding and mixing of food. The muscularis externa of the stomach is composed of the inner oblique layer, middle circular layer, and the outer longitudinal layer.
The arrangement of these proteins on the apical and basolateral sides of the epithelium determines the net movement of ions and water in the tract. H + and Cl − are secreted by the parietal cells into the lumen of the stomach creating acidic conditions with a low pH of 1. H + is pumped into the stomach by exchanging it with K +.
The stomach is involved in the gastric phase of digestion, following the cephalic phase in which the sight and smell of food and the act of chewing are stimuli. In the stomach a chemical breakdown of food takes place by means of secreted digestive enzymes and gastric acid. The stomach is located between the esophagus and the small intestine.
50-60% of total gastric acid secretion occurs during this phase. The gastric phase is a period in which swallowed food and semidigested protein (peptides and amino acids) activate gastric activity. Ingested food stimulates gastric activity in two ways: by stretching the stomach and by gastric contents stimulating receptors in the stomach. [2]
The stomach is a distensible organ and can normally expand to hold about one litre of food. [22] This expansion is enabled by a series of gastric folds in the inner walls of the stomach. The stomach of a newborn baby will only be able to expand to retain about 30 ml.
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It extracts water and salt from solid wastes before they are eliminated from the body and is the site in which the fermentation of unabsorbed material by the gut microbiota occurs. Unlike the small intestine, the colon does not play a major role in absorption of foods and nutrients. About 1.5 litres or 45 ounces of water arrives in the colon ...
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