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Left ventricular hypertrophy with secondary repolarization abnormalities as seen on ECG Histopathology of (a) normal myocardium and (b) myocardial hypertrophy. Scale bar indicates 50 μm. Gross pathology of left ventricular hypertrophy. Left ventricle is at right in image, serially sectioned from apex to near base.
Histopathology of (a) normal myocardium and (b) myocardial hypertrophy. Scale bar indicates 50 μm. Rectangular "Boxcar" nuclei is a microscopic sign indicating myocardial hypertrophy. The ventricles are the chambers in the heart responsible for pumping blood either to the lungs (right ventricle) or to the rest of the body (left ventricle).
Cardiac fibrosis is common in non-human great apes in human care. The term idiopathic myocardial fibrosis was coined to emphasize this disease is likely different from the above described forms of cardiac fibrosis in humans. The etiology is not known, though vitamin D deficiency is a potential suspected cause at least in chimpanzees. [31]
The diagnosis of left ventricular outflow tract obstruction is usually made by echocardiographic assessment and is defined as a peak left ventricular outflow tract gradient of ≥ 30 mmHg. [ 37 ] Another, non-obstructive variant of HCM is apical hypertrophic cardiomyopathy ( AHCM or ApHCM ), [ 39 ] also called Yamaguchi syndrome .
Rheumatic heart disease at autopsy with characteristic findings (thickened mitral valve, thickened chordae tendineae, hypertrophied left ventricular myocardium). Almost all cases of mitral stenosis are due to disease in the heart secondary to rheumatic fever and the consequent rheumatic heart disease.
Cardiomyopathy is a group of primary diseases of the heart muscle. [1] Early on there may be few or no symptoms. [1] As the disease worsens, shortness of breath, feeling tired, and swelling of the legs may occur, due to the onset of heart failure. [1]
Disorders of the myocardium. Cardiomyopathy – Cardiomyopathy is a deterioration of the myocardium. Several classifications have been used to categorize cardiomyopathies with the most common being primary vs. secondary, and dilated vs. restrictive vs. hypertrophic (presented below).
Inferior left ventricle wall scar, short axis echocardiography view Myocardial scarring is the accumulation of fibrous tissue resulting after some form of trauma to the cardiac tissue. [ 1 ] [ 2 ] Fibrosis is the formation of excess tissue in replacement of necrotic or extensively damaged tissue.
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