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It is a protein that in humans is encoded by gene ABCC11. [3] [4] [5] The gene is responsible for determination of human cerumen type (wet or dry ear wax) and presence of underarm osmidrosis (odor associated with sweat caused by apocrine secretion), and is associated with colostrum secretion. [6]
The ABCC11 gene determines axillary body odor and the type of earwax. [ 6 ] [ 31 ] [ 32 ] [ 33 ] The loss of a functional ABCC11 gene is caused by a 538G>A single-nucleotide polymorphism , resulting in a loss of body odor in people who are specifically homozygous for it.
Nguyen explained that body odor is primarily associated with apocrine sweat glands, found in the armpit and groin areas. ... For those without the mutation in the ABCC11 gene, protein in those ...
Body odor encompasses axillary (underarm) odor and foot odor. [1] It is caused by a combination of sweat gland secretions and normal skin microflora. [1] In addition, androstane steroids and the ABCC11 transporter are essential for most axillary odor. [1] [2] Body odor is a complex phenomenon, with numerous compounds and catalysts involved in ...
Body odor (or bromhidrosis, if you’re being technical) is “caused by bacteria on the skin, which break down sweat, giving off a foul odor,” according to Dr. Joshua Zeichner, a dermatologist ...
Body odor occurs when your body releases sweat that then comes into contact with bacteria. If you're doing everything right but still feel like your body is emitting an unpleasant odor, it may be ...
This distinction is caused by a single base change in the "ATP-binding cassette C11 gene". Dry-type individuals are homozygous for adenine (AA) whereas wet-type requires at least one guanine (AG or GG). [6] Dry earwax is gray or tan and brittle, and is about 20% lipid. [5] It has a smaller concentration of lipid and pigment granules than wet ...
Sweat and body odor are typically thought to go hand in hand, but experts say it's a little more complicated than that. Sweat alone doesn't have a smell, according to Harvard Health.