Search results
Results from the WOW.Com Content Network
Illustration showing influenza virus attaching to cell membrane via the surface protein hemagglutinin. Hemagglutinins (alternatively spelt haemagglutinin, from the Greek haima, 'blood' + Latin gluten, 'glue') are homotrimeric glycoproteins present on the protein capsids of viruses in the Paramyxoviridae and Orthomyxoviridae families.
Hemagglutinin is a class I fusion protein, [1] [2] having multifunctional activity as both an attachment factor and membrane fusion protein. Therefore, HA is responsible for binding influenza viruses to sialic acid on the surface of target cells, such as cells in the upper respiratory tract or erythrocytes , [ 3 ] resulting in the ...
Sialic acid is a negatively charged sugar associated with the protein and lipid portions of lipoproteins. [ citation needed ] To infect a host cell, the influenza virus attaches to the exterior cell surface using hemagglutinin , a molecule found on the surface of the virus that binds to sialic acid groups.
Both hemagglutinin and hemagglutinin esterase fusion protein are similar in terms of structure and the folding of individual segments. yet, only 12% amino acid are identical between HA and HEF. One significant difference between HE and HEF is the presence of an additional bulge in HEF globular domain (bottom part of the domain) which contains ...
Hemagglutinin-neuraminidase refers to a single viral protein that has both hemagglutinin and (endo) neuraminidase EC 3.2.1.18 activity. This is in contrast to the proteins found in influenza , where both functions exist but in two separate proteins.
Interlocked SS symbol or a zigzag, like a stylized lightning stroke. Prosthetic groups or inhibitors Stick figures, or ball & stick. Metals Spheres. Shading and colour Shading or colour adds dimensionality to the diagram. Generally, the features at the front are the highest in contrast and those towards the back are the lowest.
Sequence alignment of 27 H9N2 avian influenza hemagglutinin protein sequences. The top section is colored by residue conservation and the bottom by residue chemical properties. Alignment produced with ClustalW. Date: 19 July 2006: Source: Own work: Author: Opabinia regalis: Permission (Reusing this file) GDFL
The protein was found to undergo phosphorylation in the host cell. [citation needed] The M1 protein forms a layer under the patches of host cell membrane that are rich with the viral hemagglutinin, neuraminidase and M2 transmembrane proteins, and facilitates budding of the mature viruses. [citation needed]