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Aglepristone (INN Tooltip International Nonproprietary Name) (brand name Alizin; former developmental code names RU-46534, RU-534) is a synthetic, steroidal antiprogestogen related to mifepristone which is marketed by Virbac in several European countries for use in veterinary medicine.
Progestogen-only pills," "Progestin-only pills," and "Progesterone-only pills" are terms each referring to the same class of synthetic hormone medications. The phrase "Progestogen-only pill" is used by the World Health Organization and much of the international medical community. [ 7 ]
Due to the positive results, Panuce was allowed to try the pill on another of her dogs, her Newfoundland Benson, also 12, who almost couldn’t walk due to severe arthritis.
Levels of DMPA which caused malignant mammary tumors in dogs were equivalent to 25 times the amount of the normal luteal phase progesterone level for dogs. This is lower than the pregnancy level of progesterone for dogs, and is species-specific. [249]
[92] [122] However, oral progesterone achieves very low progesterone levels and has relatively weak progestogenic effects, which might be responsible for the absence of increase in VTE risk. [122] Parenteral progesterone, such as vaginal or injectable progesterone, which can achieve luteal-phase levels of progesterone and associated ...
Drospirenone is a progestin and antiandrogen medication which is used in birth control pills to prevent pregnancy and in menopausal hormone therapy, among other uses. [ 1 ] [ 10 ] It is available both alone under the brand name Slynd and in combination with an estrogen under the brand name Yasmin among others.
5α-Dihydroprogesterone (5α-DHP, allopregnanedione, [1] or 5α-pregnane-3,20-dione) is an endogenous progestogen and neurosteroid that is synthesized from progesterone. [2] [3] It is also an intermediate in the synthesis of allopregnanolone and isopregnanolone from progesterone.
OHPA is a progestogen and acts as an agonist of the progesterone receptor (PR), both PR A and PR B isoforms (IC 50 = 16.8 nM and 12.6 nM, respectively). [15] It has more than 50-fold higher affinity for the PR isoforms than 17α-hydroxyprogesterone, a little less than half the affinity of progesterone, and slightly higher affinity than OHPC. [16]