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The first fossilized evidence of sexual reproduction in eukaryotes is from the Stenian period, about 1.05 billion years old. [19] [20]Biologists studying evolution propose several explanations for the development of sexual reproduction and its maintenance.
The term stem cell was coined by Theodor Boveri and Valentin Haecker in late 19th century. [8] Pioneering works in theory of blood stem cell were conducted in the beginning of 20th century by Artur Pappenheim, Alexander A. Maximow, Franz Ernst Christian Neumann.
Progenitor cells have become a hub for research on a few different fronts. Current research on progenitor cells focuses on two different applications: regenerative medicine and cancer biology.