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  2. Glucose-6-phosphate dehydrogenase deficiency - Wikipedia

    en.wikipedia.org/wiki/Glucose-6-phosphate_de...

    Most individuals with G6PD deficiency are asymptomatic.When it induces hemolysis, it is usually is short-lived. [5]Most people who develop symptoms are male, due to the X-linked pattern of inheritance, but female carriers can be affected due to unfavorable lyonization or skewed X-inactivation, where random inactivation of an X-chromosome in certain cells creates a population of G6PD-deficient ...

  3. Methylene blue - Wikipedia

    en.wikipedia.org/wiki/Methylene_blue

    The methylene blue value is defined as the number of milliliter's standard methylene value solution decolorized 0.1 g of activated carbon (dry basis). [65] Methylene blue value reflects the amount of clay minerals in aggregate samples. [ 66 ]

  4. Glucose-6-phosphate dehydrogenase - Wikipedia

    en.wikipedia.org/wiki/Glucose-6-phosphate_de...

    Yeast G6PD is inhibited by long chain fatty acids according to two older publications [14] [15] and might be product inhibition in fatty acid synthesis which requires NADPH. G6PD is negatively regulated by acetylation on lysine 403 (Lys403), an evolutionarily conserved residue. The K403 acetylated G6PD is incapable of forming active dimers and ...

  5. Methemoglobinemia - Wikipedia

    en.wikipedia.org/wiki/Methemoglobinemia

    Genetically induced chronic low-level methemoglobinemia may be treated with oral methylene blue daily. Also, vitamin C can occasionally reduce cyanosis associated with chronic methemoglobinemia, and may be helpful in settings in which methylene blue is unavailable or contraindicated (e.g., in an individual with G6PD deficiency). [22]

  6. Heinz body - Wikipedia

    en.wikipedia.org/wiki/Heinz_body

    G6PD deficient red cells in combination with high levels of oxidants causes a cross-linking of sulfhydryl groups on globin chains which causes a denaturing and formation of Heinz body precipitates. [8] Heinz bodies can also be found in chronic liver disease. [9] Alpha-thalassemia. Normal adult hemoglobin is composed of two alpha and two beta ...

  7. 6-phosphogluconate dehydrogenase deficiency - Wikipedia

    en.wikipedia.org/wiki/6-phosphogluconate_de...

    The most important measure taken for treatment of 6-phosphoglucanate dehydrogenase is prevention. Avoidance of chemical exposures to drugs and foods that have the potential to cause hemolysis. Although some foods and supplements have antioxidant properties, their use does not decrease the severity of G6PD deficiency. [citation needed]

  8. Normocytic anemia - Wikipedia

    en.wikipedia.org/wiki/Normocytic_anemia

    a B2 deficiency [3] a B6 deficiency [3] or a mixture of conditions producing microcytic and macrocytic anemia. [1] Blood loss, suppressed production of RBCs or hemolysis represent most cases of normocytic anemia. In blood loss, morphologic findings are generally unremarkable, except after 12 to 24 hrs where polychromasia appears.

  9. Chromopertubation - Wikipedia

    en.wikipedia.org/wiki/Chromopertubation

    Allergic-like reactions and methemoglobinemia have been documented after the use of methylene blue dye in chromopertubation. [9] These reported symptoms vary from blue discoloration of body fluids to anaphylactic shock. [10] Methemoglobinemia is a blood disorder that can potentially result in various levels of cyanosis. [11]

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