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Glucocorticoid potency Mineralocorticoid potency Terminal half-life (hours) Cortisol (hydrocortisone) 1 1 8 Cortisone: 0.8 0.8 8 Prednisone: 3.5–5 0.8 16–36 Prednisolone: 4 0.8 16–36 Methylprednisolone: 5–7.5 0.5 18–40 Dexamethasone: 25–80 0 36–54 Betamethasone: 25–30 0 36–54 Triamcinolone: 5 0 12–36 Deflazacort: 6.5 – 1.3
Dexamethasone is a fluorinated glucocorticoid medication [10] used to treat rheumatic problems, a number of skin diseases, severe allergies, asthma, chronic obstructive pulmonary disease (COPD), croup, brain swelling, eye pain following eye surgery, superior vena cava syndrome (a complication of some forms of cancer), [11] and along with antibiotics in tuberculosis. [10]
ATC code D07 Corticosteroids, dermatological preparations is a therapeutic subgroup of the Anatomical Therapeutic Chemical Classification System, a system of alphanumeric codes developed by the World Health Organization (WHO) for the classification of drugs and other medical products.
Topical steroids are the topical forms of corticosteroids.Topical steroids are the most commonly prescribed topical medications for the treatment of rash and eczema.Topical steroids have anti-inflammatory properties and are classified based on their skin vasoconstrictive abilities. [1]
Methylprednisolone (Depo-Medrol, Medrol, Solu-Medrol) is a synthetic glucocorticoid, primarily prescribed for its anti-inflammatory and immunosuppressive effects. [4] [5] [6] It is either used at low doses for chronic illnesses or used concomitantly at high doses during acute flares.
Dexamethasone and its derivatives are almost pure glucocorticoids, while prednisone and its derivatives have some mineralocorticoid action in addition to the glucocorticoid effect. Fludrocortisone (Florinef) is a synthetic mineralocorticoid.
Steroid ring system.. This is a list of corticosteroids (glucocorticoids and mineralocorticoids) or derivatives of cortisol (hydrocortisone).Most esters of these corticosteroids are not included in this list; for esters, see here instead.
Methylprednisolone acetate, sold under the brand names Depo-Medrol among others, is a synthetic glucocorticoid corticosteroid and a corticosteroid ester—specifically the C21 acetate ester of methylprednisolone—which is used in clinical and veterinary medicine.
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