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Donepezil, sold under the brand name Aricept among others, is a medication used to treat dementia of the Alzheimer's type. [ 3 ] [ 4 ] [ 8 ] It appears to result in a small benefit in mental function and ability to function. [ 9 ]
Currently, there is no way to stop or slow the development of chronic traumatic encephalopathy (CTE). However, medications like Aricept (donepezil) and Namenda (memantine) can mitigate memory loss and confusion, and Aricept can improve memory, motivation, and attention by increasing acetylcholine levels in the brain.
“Limbic” is related to the brain areas first involved, “age-related” and the name “LATE” itself refer to the onset of disease usually in persons aged 80 or older. “ TDP-43 ” indicates the aberrant mis-folded protein (or proteinopathy ) deposits in the brain that characterize LATE, and “ encephalopathy ” means illness of brain.
Aricept – used to slow the progression of Alzheimer's disease Ativan ( lorazepam ) – a benzodiazepine , used to treat anxiety Asendin ( amoxapine ) – an dibenzoxazepine antidepressant
Aribit (Aripiprazole) tablets. Aripiprazole, sold under the brand names Abilify and Aristada, among others, is an atypical antipsychotic [8] primarily used in the treatment of schizophrenia, bipolar disorder, and irritability associated with autism spectrum disorder; [8] other uses include as an add-on treatment for major depressive disorder and tic disorders. [8]
Chlorpromazine, an antipsychotic and antiemetic drug which is classed as a "major" tranquilizer, may cause paradoxical effects such as agitation, hallucinations, excitement, insomnia, bizarre dreams, aggravation of psychotic symptoms and toxic confusional states. [8] These may be more common in elderly dementia patients.
In the elderly, long-term benzodiazepine therapy is a risk factor for amplifying cognitive decline, [29] although gradual withdrawal is associated with improved cognitive status. [30] A study of alprazolam found that 8 weeks administration of alprazolam resulted in deficits that were detectable after several weeks but not after 3.5 years.
Other dopamine antagonists and antiemetics can cause tardive dyskinesia, such as metoclopramide and promethazine, used to treat gastrointestinal disorders. Atypical antipsychotics are considered lower-risk for causing TD than their typical counterparts, with incidence rates of 13.1% and 32.4% respectively in short-term trials primarily ...