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Chemotherapy-induced acral erythema, also known as palmar-plantar erythrodysesthesia or hand-foot syndrome is reddening, swelling, numbness and desquamation (skin sloughing or peeling) on palms of the hands and soles of the feet (and, occasionally, on the knees, elbows, and elsewhere) that can occur after chemotherapy in patients with cancer.
Adverse drug reaction: palmoplantar erythrodysesthesia (acral erythema) Because circulating levels of estrogen increase in both cirrhosis and pregnancy, estrogen was thought to be the main cause for the increased vascularity. More recently, nitric oxide has also been implicated in the pathogenesis of palmar erythema. [5]
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Calluses (plantar in right foot and medial in left foot) A callus (pl.: calluses) is an area of thickened and sometimes hardened skin that forms as a response to repeated friction, pressure, or other irritation. Since repeated contact is required, calluses are most often found on the feet and hands, but they may occur anywhere on the skin.
the sural region encompassing the back of the lower leg, the calcaneal region encompassing the heel, the plantar region encompassing the sole of the foot. Some regions are combined into larger regions. These include the trunk, which is a combination of the thoracic, mammary, abdominal, navel, and coxal regions.
The pisiform bone is most recognizable as an unassuming palmar projection forming the heel of human hand. [2]The pisiform bone, along with the hamulus of the hamate, defines the medial boundary of the carpal tunnel [2] because the pisiform body acts as one of the four attachments points of the flexor retinaculum. [3]
Corns from an acute injury, such as from a thorn in the sole of the foot, may form due to the weight of the body, when the process that creates the usually evenly developing plantar callus is concentrated at the point of the healing injury, as an internal callus may be triggered by pressure on the transitional scar tissue. Once formed, the corn ...
The anatomy and composition of the plantar plates are similar to the palmar plates in the metacarpophalangeal (MCP) and interphalangeal joints in the hand; the proximal origin is thin but the distal insertion is stout. Due to the weight-bearing nature of the human foot, the plantar plates are exposed to extension forces not present in the human ...