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Chemotherapy-induced acral erythema, also known as palmar-plantar erythrodysesthesia or hand-foot syndrome is reddening, swelling, numbness and desquamation (skin sloughing or peeling) on palms of the hands and soles of the feet (and, occasionally, on the knees, elbows, and elsewhere) that can occur after chemotherapy in patients with cancer.
Adverse drug reaction: palmoplantar erythrodysesthesia (acral erythema) Because circulating levels of estrogen increase in both cirrhosis and pregnancy, estrogen was thought to be the main cause for the increased vascularity. More recently, nitric oxide has also been implicated in the pathogenesis of palmar erythema. [5]
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Calluses (plantar in right foot and medial in left foot) A callus (pl.: calluses) is an area of thickened and sometimes hardened skin that forms as a response to repeated friction, pressure, or other irritation. Since repeated contact is required, calluses are most often found on the feet and hands, but they may occur anywhere on the skin.
Allen's test: Edgar Van Nuys Allen: vascular surgery, critical care [1] arterial supply of the hand: tests for presence of palmar ulnar-radial anastomosis (palmar arch) Apgar score: Virginia Apgar: obstetrics, pediatrics: assess health of newborn Apley grind test: Alan Graham Apley: orthopaedic surgery: meniscal lesions: manoeuvres to elicit ...
Corns from an acute injury, such as from a thorn in the sole of the foot, may form due to the weight of the body, when the process that creates the usually evenly developing plantar callus is concentrated at the point of the healing injury, as an internal callus may be triggered by pressure on the transitional scar tissue. Once formed, the corn ...
The plantar plate is firm but flexible fibrocartilage with a composition similar to that found in the menisci of the knee (composed roughly of 75% type-I collagen), and can thus withstand compressive loads and act as a supportive articular surface. Most of its fibers are oriented longitudinally, in the same direction as the plantar fascia, and ...
Mulder's sign is a physical exam finding associated with Morton's neuroma, which may be elicited while the patient is in the supine position on the examination table. The pain of the neuroma, as well as a click, can be produced by squeezing the two metatarsal heads together with one hand, while concomitantly putting pressure on the interdigital space with the other hand.