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The lacrimal gland is a compound tubuloacinar gland, it is made up of many lobules separated by connective tissue, each lobule contains many acini.The acini composed of large serous cells which, produce a watery serous secretion, serous cells are filled with lightly stained secretory granules and surrounded by well-developed myoepithelial cells and a sparse, vascular stroma.
These may be positive for alpha smooth muscle actin and can contract and expel the secretions of exocrine glands. They are found in the sweat glands, mammary glands, lacrimal glands, and salivary glands. Myoepithelial cells in these cases constitute the basal cell layer of an epithelium that harbors the epithelial progenitor.
The lacrimal apparatus is the physiological system containing the orbital structures for tear production and drainage. [1]It consists of: The lacrimal gland, which secretes the tears, and its excretory ducts, which convey the fluid to the surface of the eye; it is a j-shaped serous gland located in lacrimal fossa.
The acini are surrounded, sometimes incompletely, by a row of myoepithelial cells. Animal studies suggest that the ducts of Wolfring glands have a tortuous course and open onto the palpebral conjunctiva. Like the main lacrimal gland, the accessory lacrimal glands are also densely innervated, but they lack parasympathetic innervation.
Microscopic anatomy is the study of minute anatomical structures assisted with microscopes, and includes histology (the study of the organization of tissues), and cytology (the study of cells). The Anatomy Lesson of Dr. Nicolaes Tulp , by Rembrandt ; depicts an anatomy demonstration using a cadaver .
The lacrimal sac or lachrymal sac [1] is the upper dilated end of the nasolacrimal duct, [2] and is lodged in a deep groove formed by the lacrimal bone and frontal process of the maxilla. It connects the lacrimal canaliculi , which drain tears from the eye's surface, and the nasolacrimal duct , which conveys this fluid into the nasal cavity. [ 3 ]
Historically, bilateral parotid and lacrimal gland enlargement was characterized by the term Mikulicz's disease if the enlargement appeared apart from other diseases. If it was secondary to another disease, such as tuberculosis, sarcoidosis, lymphoma, and Sjögren's syndrome, the term used was Mikulicz's syndrome.
Mucoepidermoid carcinoma (MEC) [1] is the most common type of minor salivary gland malignancy in adults. Mucoepidermoid carcinoma can also be found in other organs, such as bronchi, lacrimal sac, [2] and thyroid gland. Mucicarmine staining is one stain used by pathologist for detection. [3]