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Among the AChEIs, donepezil and rivastigmine can help reduce neuropsychiatric symptoms [6] and improve the frequency and severity of hallucinations in the less severe stages of DLB. [61] For treating psychosis and agitation in DLB, there is low evidence for memantine, olanzapine and aripiprazole , and very low evidence for the efficacy of ...
Donepezil, sold under the brand name Aricept among others, is a medication used to treat dementia of the Alzheimer's type. [3] [4] [8] It appears to result in a small benefit in mental function and ability to function. [9] Use, however, has not been shown to change the progression of the disease. [10] Treatment should be stopped if no benefit ...
Memantine/donepezil, sold under the brand name Namzaric among others, is a fixed dose combination medication used for the treatment of dementia of the Alzheimer's type. [1] It contains memantine, as the hydrochloride, a NMDA receptor antagonist; and donepezil as the hydrochloride, an acetylcholinesterase inhibitor. [1] It is taken by mouth. [1]
Researchers found that patients with musical hallucinations respond well to the drug Donepezil, making it another potential treatment for the condition. Donepezil, which belongs to a class of medication called acetylcholinesterase inhibitors , is most commonly used to treat dementia in patients with Alzheimer's disease.
Serax – anti-anxiety medication of the benzodiazepine class, often used to help during detoxification from alcohol or other addictive substances; Serentil (mesoridazine) – an antipsychotic drug used in the treatment of schizophrenia [1]
Reported adverse events with memantine are infrequent and mild, including hallucinations, confusion, dizziness, headache and fatigue. [196] [197] The combination of memantine and donepezil [198] has been shown to be "of statistically significant but clinically marginal effectiveness". [199]
The visual hallucinations in DLB are generally vivid hallucinations of people or animals and they often occur when someone is about to fall asleep or wake up. Other prominent symptoms include problems with planning (executive function) and difficulty with visual-spatial function, [ 13 ] and disruption in autonomic bodily functions . [ 78 ]
Memantine when added to donepezil in those with moderate-to-severe dementia resulted in "limited improvements" in a 2017 review. [24] The UK National Institute for Clinical Excellence (NICE) issued guidance in 2018 recommending consideration of the combination of memantine with donepezil in those with moderate-to-severe dementia.
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