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II III IV Oral LD 50: Up to and including 50 mg/kg From 50 to 500 mg/kg From 500 to 5000 mg/kg Greater than 5000 mg/kg Inhalation LC50 Up to and including 0.2 mg/L From 0.2 to 2 mg/L From 2. to 20 mg/L Greater than 20 mg/L Dermal LD50 Up to and including 200 mg/kg From 200 to 2000 mg/kg From 2000 to 20,000 mg/kg Greater than 20,000 mg/kg
Class II: moderately hazardous; Class III: slightly hazardous; The system is based on LD50 determination in rats, thus an oral solid agent with an LD50 at 5 mg or less/kg bodyweight is Class Ia, at 5–50 mg/kg is Class Ib, LD50 at 50–2000 mg/kg is Class II, and at LD50 at the concentration more than 2000 mg/kg is classified as Class III.
The oral bioavailability of gabapentin enacarbil (as gabapentin) is greater than or equal to 68%, across all doses assessed (up to 2,800 mg), with a mean of approximately 75%. [ 25 ] [ 1 ] In contrast to the other gabapentinoids, the pharmacokinetics of phenibut have been little-studied, and its oral bioavailability is unknown. [ 28 ]
Toxicity labels [1] viz; red label, yellow label, blue label and green label are mandatory labels employed on pesticide containers in India identifying the level of toxicity (that is, the toxicity class) of the contained pesticide. [1] [2] [3] The schemes follows from the Insecticides Act of 1968 [1] and the Insecticides Rules of 1971.
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A major grower said this week it was abandoning its citrus growing operations, reflecting the headwinds Florida's signature crops are facing following a series of hurricanes and tree diseases.
An auxiliary label (also called cautionary and advisory label or prescription drug warning label) is a label added on to a dispensed medication package by a pharmacist in addition to the usual prescription label. These labels are intended to provide supplementary information regarding the safe administration, use, and storage of the medication. [1]
U.S. President-elect Donald Trump on Saturday demanded that BRICS member countries commit to not creating a new currency or supporting another currency that would replace the United States dollar ...