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Sertraline for Depression & Anxiety: Breaking Down the Side Effects. If your mental health has seemed a little out of sorts for some time now, there’s a chance you’ve already spoken to a ...
Funny Inspirational Quotes About Love and Marriage “Before you marry a person, you should first make them use a computer with slow internet to see who they really are.”
Sertraline, sold under the brand name Zoloft among others, is an antidepressant of the selective serotonin reuptake inhibitor (SSRI) class. [10] The effectiveness of sertraline for depression is similar to that of other antidepressants such as Fluoxetine or Paroxetine. Sertraline is better tolerated than the older tricyclic antidepressants.
[187] [188] Fluvoxamine is an agonist of the σ 1 receptor, while sertraline is an antagonist of the σ 1 receptor, and paroxetine does not significantly interact with the σ 1 receptor. [187] [188] None of the SSRIs have significant affinity for the σ 2 receptor. [187] [188] Fluvoxamine has by far the strongest activity of the SSRIs at the σ ...
Switching From Zoloft to Prozac: Final Thoughts. Thinking about swapping out your current medication for a new antidepressant is a big decision — but you don’t have to do it alone. With the ...
Sertraline was approved for medical use in the United States for depression and other conditions in 1991 and soon became one of the most prescribed psychiatric medications in the US. [5] Koe held 14 U.S. patents and authored or co-authored 150 technical articles, but the discovery of sertraline was the highlight of his career.
Sertraline has about 60 times more potent inhibition potential on 5-HT than either NE or DA re-uptake. It is possible that only modest inhibition of DAT and NET is needed to cause an increase in energy, motivation and concentration, specially when added to other activity such as SERT inhibition. [ 18 ]
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