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  2. Sertraline for Depression & Anxiety: What Are the Possible ...

    www.aol.com/sertraline-depression-anxiety...

    Sertraline for Depression & Anxiety: Breaking Down the Side Effects. If your mental health has seemed a little out of sorts for some time now, there’s a chance you’ve already spoken to a ...

  3. Sertraline - Wikipedia

    en.wikipedia.org/wiki/Sertraline

    Sertraline, sold under the brand name Zoloft among others, is an antidepressant of the selective serotonin reuptake inhibitor (SSRI) class. [10] The effectiveness of sertraline for depression is similar to that of other antidepressants such as Fluoxetine or Paroxetine. Sertraline is better tolerated than the older tricyclic antidepressants.

  4. Second-generation antidepressant - Wikipedia

    en.wikipedia.org/wiki/Second-generation...

    The term "third generation antidepressant" is sometimes used to refer to newer antidepressants, [1] from the 1990s and 2000s, often selective serotonin reuptake inhibitors (SSRIs) such as; fluoxetine (Prozac), paroxetine (Paxil) and sertraline (Zoloft), as well as some non-SSRI antidepressants such as mirtazapine, nefazodone, venlafaxine ...

  5. Selective serotonin reuptake inhibitor - Wikipedia

    en.wikipedia.org/wiki/Selective_serotonin...

    [187] [188] Fluvoxamine is an agonist of the σ 1 receptor, while sertraline is an antagonist of the σ 1 receptor, and paroxetine does not significantly interact with the σ 1 receptor. [187] [188] None of the SSRIs have significant affinity for the σ 2 receptor. [187] [188] Fluvoxamine has by far the strongest activity of the SSRIs at the σ ...

  6. Is It Time to Switch from Zoloft to Prozac? How to Tell

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    Switching From Zoloft to Prozac: Final Thoughts. Thinking about swapping out your current medication for a new antidepressant is a big decision — but you don’t have to do it alone. With the ...

  7. Switching Antidepressants: Safety, Side Effects & Other ... - AOL

    www.aol.com/switching-antidepressants-safety...

    Before you get overwhelmed by the details, let’s get our priorities straight and our message clear: You can switch your antidepressant treatment safely, but you’ll have to follow a smart ...

  8. Development and discovery of SSRI drugs - Wikipedia

    en.wikipedia.org/wiki/Development_and_discovery...

    Sertraline has about 60 times more potent inhibition potential on 5-HT than either NE or DA re-uptake. It is possible that only modest inhibition of DAT and NET is needed to cause an increase in energy, motivation and concentration, specially when added to other activity such as SERT inhibition. [ 18 ]

  9. Can Zoloft & Other SSRIs Cause "Intimate" Side Effects?

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    Zoloft is often prescribed off-label to treat PE, because it can make climaxing take longer. Zoloft works by increasing serotonin levels, which can cause side effects such as difficulty with ...

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