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The Draize test is an acute toxicity test devised in 1944 by Food and Drug Administration (FDA) toxicologists John H. Draize and Jacob M. Spines. Initially used for testing cosmetics, the procedure involves applying 0.5 mL or 0.5 g of a test substance to the eye or skin of a restrained, conscious animal, and then leaving it for a set amount of time before rinsing it out and recording its effects.
"Typically, animal tests for cosmetics include skin and eye irritation tests where chemicals are rubbed onto the shaved skin or dripped into the eyes of rabbits; repeated oral force-feeding studies lasting weeks or months to look for signs of general illness or specific health hazards, such as cancer or birth defects; and even widely condemned ...
The term "rabbit test" was first recorded in 1949, and was the origin of a common euphemism, "the rabbit died", for a positive pregnancy test. [4] The phrase was, in fact, based on a common misconception about the test. While many people assumed that the injected rabbit would die only if the woman was pregnant, in fact all rabbits used for the ...
Over 20,000 rabbits were used for animal testing in the UK in 2004. [119] Albino rabbits are used in eye irritancy tests (Draize test) because rabbits have less tear flow than other animals, and the lack of eye pigment in albinos make the effects easier to visualize. The numbers of rabbits used for this purpose has fallen substantially over the ...
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The hCG test can be used to screen for uterus cancer, or a molar pregnancy, which is when there is abnormal placental growth in the uterus. [9] The hCG test can also be done after a miscarriage to ensure that a molar pregnancy is not present. In men, the hCG test can be used to screen for the presence of testicular cancer. [9]
Scleral tattooing. Scleral tattooing is the practice of tattooing the sclera, or white part, of the human eye.Rather than being injected into the tissue, the dye is injected between two layers of the eye, then gradually spreads.
Any rabbit suspected of having myxomatosis should be immediately isolated, and all rabbits in the area moved indoors. To prevent the virus from spreading further any cages and cage furnishings that have come into contact with infected rabbits should be disinfected, and owners should disinfect their hands between rabbits.