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Oncogenomics is a sub-field of genomics that characterizes cancer-associated genes.It focuses on genomic, epigenomic and transcript alterations in cancer. Cancer is a genetic disease caused by accumulation of DNA mutations and epigenetic alterations leading to unrestrained cell proliferation and neoplasm formation.
A proto-oncogene is a normal gene that could become an oncogene due to mutations or increased expression. Proto-oncogenes code for proteins that help to regulate the cell growth and differentiation. Proto-oncogenes are often involved in signal transduction and execution of mitogenic signals, usually through their protein products.
The chance of cancer cannot be reduced by removing proto-oncogenes from the genome, even if this were possible, as they are critical for the growth, repair, and homeostasis of the organism. It is only when they become mutated that the signals for growth become excessive. One of the first oncogenes to be defined in cancer research is the ras ...
On Dec. 7 at North Henderson High School, 11th grader Citlally Diaz, 17, was honored for winning one of just four $3,000 scholarship grand prize awards out of thousands of entries across the country.
A tumor suppressor gene (TSG), or anti-oncogene, is a gene that regulates a cell during cell division and replication. [1] If the cell grows uncontrollably, it will result in cancer . When a tumor suppressor gene is mutated, it results in a loss or reduction in its function.
Lung cancer is the second most common type of cancer and leading cause of death in men and women in the United States, it is estimated that there is about 216,000 new cases and 160,000 deaths due to lung cancer. [116] Initiation and progression of lung carcinoma is the result of the interaction between genetic, epigenetic and environmental factors.
The Leukemia & Lymphoma Society (LLS), a 501(c)(3) charitable organization founded in 1949, is a voluntary health organization dedicated to fighting blood cancer world-wide. LLS funds blood cancer research on cures for leukemia , lymphoma , Hodgkin's disease , and myeloma .
Harold Eliot Varmus (born December 18, 1939) is an American Nobel Prize-winning scientist.He is currently the Lewis Thomas University Professor of Medicine at Weill Cornell Medicine and a senior associate at the New York Genome Center.