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Pneumocystis jirovecii (previously P. carinii) is a yeast-like fungus of the genus Pneumocystis. The causative organism of Pneumocystis pneumonia , it is an important human pathogen , particularly among immunocompromised hosts .
Pneumocystis pneumonia (PCP), also known as Pneumocystis jirovecii pneumonia (PJP), is a form of pneumonia that is caused by the yeast-like fungus Pneumocystis jirovecii. [ 3 ] [ 4 ] Pneumocystis specimens are commonly found in the lungs of healthy people although it is usually not a cause for disease. [ 5 ]
X-ray and CT of ground glass opacities and pneumothorax in pneumocystis pneumonia. Diagnosis of Pneumocystis pneumonia is by identifying the organism from a sample of sputum, fluid from affected lungs or a biopsy. [4] [3] A chest X-ray of affected lungs show widespread shadowing in both lungs, with a "bat-wing" pattern and ground glass appearance.
It includes the single order Pneumocystidales, which contains the single monotypic family Pneumocystidaceae, which in turn contains the genus Pneumocystis, causative agent of Pneumocystis pneumonia. References
Micrograph showing a Masson body (off center left/bottom of the image – pale circular and paucicellular), as may be seen in cryptogenic organizing pneumonia. The Masson body plugs the airway. The artery associated with the obliterated airway is also seen (far left of the image). H&E stain. Specialty: Pulmonology Symptoms
Pneumocystis murina is unique for several reasons. Firstly, it is only found in laboratory mice, not in natural environments. [7] Secondly, it is a pathogen that causes cyst formation in the respiratory tract of immunocompromised lab mice, leading to clinical signs of infection such as dyspnea, weight loss, hunched posture, and scaly skin. [6]
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The name Pneumocystis jiroveci, which is now corrected to Pneumocystis jirovecii, was proposed as a new name only for the human form previously identified as Pneumocystis carinii. Not all of Pneumocystis carinii is named Pneumocystis jirovecii. The name Pneumocystis carinii still applies to a rat parasite. Other taxa formerly classified as ...