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Multinucleate cells (also known as multinucleated cells or polynuclear cells) are eukaryotic cells that have more than one nucleus, i.e., multiple nuclei share one common cytoplasm. Mitosis in multinucleate cells can occur either in a coordinated, synchronous manner where all nuclei divide simultaneously or asynchronously where individual ...
The eukaryotic cell cycle is very complex and is one of the most studied topics, since its misregulation leads to cancers. It is possibly a good example of a mathematical model as it deals with simple calculus but gives valid results. Two research groups [1] [2] have produced several models of the cell cycle simulating several organisms. They ...
It binds to ligand CD70, and plays a key role in regulating B-cell activation and immunoglobulin synthesis. [5] When CD27 binds CD70, a signaling cascade leads to the differentiation and clonal expansion of T cells. [11] The cascade also results in improved survival and memory of cytotoxic T cells and increased production of certain cytokines. [12]
Modelling biological systems is a significant task of systems biology and mathematical biology. [a] Computational systems biology [b] [1] aims to develop and use efficient algorithms, data structures, visualization and communication tools with the goal of computer modelling of biological systems.
A mesokaryote or mesokaryotic organism is a single-celled eukaryote that shows intermediate resemblance to both prokaryotes and 'higher' eukaryotes. The term originates from a 1965 hypothesis by John David Dodge, who proposed that certain eukaryotes (mainly dinoflagellates) with closed mitosis and other traits considered 'primitive' were an intermediate step between prokaryotes and the ...
A monograph on this topic summarizes an extensive amount of published research in this area up to 1986, [19] [20] [21] including subsections in the following areas: computer modeling in biology and medicine, arterial system models, neuron models, biochemical and oscillation networks, quantum automata, quantum computers in molecular biology and ...
The Ising model is a prototypical example, in which each cell can be in either of two states called "up" and "down", making an idealized representation of a magnet. By adjusting the parameters of the model, the proportion of cells being in the same state can be varied, in ways that help explicate how ferromagnets become demagnetized when heated.
A biological model is an organism or system representing a more complex biological entity. It may refer to: a model organism, a non-human species that is extensively studied to understand particular biological phenomena present in many related organisms; an in vitro model system, representing complex in vivo systems